Magnetoencephalographic fields from patients with spontaneous and induced migraine aura
Magnetoencephalographic fields from patients with spontaneous and induced migraine aura
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DOI：
10.1002/ana.1293
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发表时间：
2001-11-01
影响因子：
11.2
通讯作者：
Welch, KMA
中科院分区：
文献类型：
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作者：
Bowyer, SM;Aurora, SK;Welch, KMA
我们调查和表征脑磁图波形的患者在自发性和视觉诱发偏头痛先兆。在4例偏头痛患者的偏头痛先兆的自发发作期间测量直流神经磁场，并与8例偏头痛先兆患者和6例正常对照者在视觉刺激枕叶皮层期间的记录进行比较。复杂的直流脑磁图的变化，类似的波形，观察到自发性和视觉诱发偏头痛患者，但在对照组。二维反向成像显示自发性和视觉诱发的偏头痛先兆患者的多个皮质区域被激活。在正常受试者中，激活。只在初级视觉皮层中观察到。结果支持一个扩散，抑郁样的神经电事件发生在偏头痛先兆，可以自发地出现或视觉触发的过度兴奋枕叶皮层的广泛地区。
We investigate and characterize the magnetoencephalographic waveforms from patients during spontaneous and visually induced migraine aura. Direct current neuromagnetic fields were measured during spontaneous onset of migraine auras in 4 migraine patients, and compared with recordings from 8 migraine-with-aura patients and 6 normal controls during visual stimulation of the occipital cortex. Complex direct current magnetoencephalographic shifts, similar in waveform, were observed in spontaneous and visually induced migraine patients; but not in controls. Two-dimensional inverse imaging showed multiple cortical areas activated in spontaneous and visually induced migraine aura patients. In normal subjects, activation was. only observed in the primary visual cortex. Results support a spreading, depression-like neuroelectric event occurring during migraine aura that can arise spontaneously or be visually triggered in widespread regions of hyperexcitable occipital cortex.