Sites of termination and relay of pulmonary rapidly adapting receptors as studied by spike-triggered averaging.

Sites of termination and relay of pulmonary rapidly adapting receptors as studied by spike-triggered averaging.
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通过尖峰触发平均研究肺部快速适应受体的终止和中继位点。

DOI:
10.1016/0006-8993(88)91615-0
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发表时间:
1988
期刊:
影响因子:
2.9
通讯作者:
Davies,RO
Davies,RO
中科院分区:
医学3区
文献类型:
--
作者:
Kubin,L;Davies,RO

文献摘要

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肺快速适应受体(RARs)神经元在猫孤束核内产生的胞外场电位的平均化,确定了RARs的终止和传递部位。机械刺激肺感受野时,在结状神经节细胞外记录单个RARs的动作电位,并将其作为平均值的触发器。平均记录(2000-4000次扫描)显示存在终末和局灶性突触电位。这些电位表明记录部位存在突触前和突触后成分,在同侧的尾侧内侧亚核和连合亚核中发现,对侧在连合亚核中发现。
The sites of termination and relay of pulmonary rapidly-adapting receptors (RARs) were determined by averaging the extracellular field potentials produced in the nucleus tractus solitarii of the cat by individual RAR neurons. Action potentials of individual RARs were recorded extracellularly in the nodose ganglion during mechanical stimulation of the receptive field in the lung and used as triggers for the averaging. The averaged records (2000–4000 sweeps) revealed the presence of terminal and focal synaptic potentials. These potentials, indicating the presence of pre- and postsynaptic elements at the recording site, were found ipsilaterally in the caudal medial and commissural subnuclei and contralaterally in the commissural subnucleus.