Social inequality and incidence of and survival from Hodgkin lymphoma, non-Hodgkin lymphoma and leukaemia in a population-based study in Denmark, 1994-2003

Social inequality and incidence of and survival from Hodgkin lymphoma, non-Hodgkin lymphoma and leukaemia in a population-based study in Denmark, 1994-2003
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DOI:
10.1016/j.ejca.2008.06.011
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发表时间:
2008-09-01
影响因子:
8.4
通讯作者:
Mellemkjcer, Lene
Mellemkjcer, Lene
中科院分区:
医学1区
文献类型:
--
作者:
Roswall, Nina;Olsen, Anja;Mellemkjcer, Lene

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我们利用全国登记处的信息,调查了丹麦 1994 年至 2003 年诊断出的社会经济、人口和健康相关指标对血液癌症发病率和生存率的影响,并随访至 2006 年。该分析基于 1925 年至 1973 年间出生且年龄≥30 岁的 322 万人队列中的 636 名霍奇金淋巴瘤 (HL) 患者、4516 名非霍奇金淋巴瘤 (NHL) 患者和 3486 名白血病患者的数据。不同社会经济地位的发病率没有一致的差异,但发现与合并症存在关联。社会经济地位最低的群体和患有其他严重疾病的患者,尤其是男性,NHL 的生存率较差。白血病的生存结果往往与 NHL 的生存结果相似,尽管相关性通常较弱且不显着。因此,社会经济地位与这些癌症的发病率之间没有很强的关联。 NFIL 后的生存可能会受到影响。 (C) 2008 Elsevier Ltd. 保留所有权利。
We investigated the effects of socioeconomic, demographic and health-related indicators on the incidence of and survival from haematological cancers diagnosed in 1994-2003 with follow-up through 2006 in Denmark using information from nationwide registers. The analyses were based on data on 636 patients with Hodgkin lymphorna (HL), 4516 with non-Hodgkin lymphoma (NHL) and 3486 with leukaemia in a cohort of 3.22 million people born between 1925 and 1973 and aged >=,30 years. No consistent differences in incidence were seen by socioeconomic position, but an association with comorbidity was found. Patients in the lowest socioeconomic groups and those with other serious illnesses, especially men, had a worse survival of NHL. Survival results for leukaemia tended to be similar to those for NHL, although associations were generally weaker and insignificant. Thus, there were no strong associations between socioeconomic position and the incidence of these cancers; survival after NFIL might be affected. (C) 2008 Elsevier Ltd. All rights reserved.