Nosocomial transmission and outbreaks of coronavirus disease 2019: the need to protect both patients and healthcare workers.

Nosocomial transmission and outbreaks of coronavirus disease 2019: the need to protect both patients and healthcare workers.
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DOI:
10.1186/s13756-020-00875-7
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发表时间:
2021-01-06
影响因子:
5.5
通讯作者:
Harbarth S
Harbarth S
中科院分区:
医学2区
文献类型:
--
作者:
Abbas M;Robalo Nunes T;Martischang R;Zingg W;Iten A;Pittet D;Harbarth S

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编制有关严重急性呼吸系统综合症冠状病毒2(SARS-CoV-2)院内爆发的最新报告,评估医护人员在传播过程中所扮演的角色,以及评估爆发管理措施。叙事性文献综述。2019年冠状病毒病(新冠肺炎)大流行给世界各地的医院和医疗保健提供者带来了巨大的负担,这增加了医院内传播和向“非冠状病毒”患者或居民以及卫生工作者爆发的风险,就死亡率而言,非冠状病毒患者或居民是最高风险人群。迄今为止,关于SARS-CoV-2医院暴发疫情的报道很多,虽然发病率各不相同,但高达60%,死亡率很高。目前关于传播动力学的证据很少,特别是利用基因组测序,而且HW在启动或放大医院内暴发中的作用还没有阐明。对病毒性呼吸道暴发的管理做法发生了范式转变,包括对患者(或居民)和包括无症状个人在内的医务工作者进行广泛的检测。这些扩大的检测标准似乎对识别和控制疫情至关重要。
To compile current published reports on nosocomial outbreaks of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), evaluate the role of healthcare workers (HCWs) in transmission, and evaluate outbreak management practices. Narrative literature review. The coronavirus disease 2019 (COVID-19) pandemic has placed a large burden on hospitals and healthcare providers worldwide, which increases the risk of nosocomial transmission and outbreaks to “non-COVID” patients or residents, who represent the highest-risk population in terms of mortality, as well as HCWs. To date, there are several reports on nosocomial outbreaks of SARS-CoV-2, and although the attack rate is variable, it can be as high as 60%, with high mortality. There is currently little evidence on transmission dynamics, particularly using genomic sequencing, and the role of HCWs in initiating or amplifying nosocomial outbreaks is not elucidated. There has been a paradigm shift in management practices of viral respiratory outbreaks, that includes widespread testing of patients (or residents) and HCWs, including asymptomatic individuals. These expanded testing criteria appear to be crucial in identifying and controlling outbreaks.
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