MAGNETIC INDUCTION HYPERTHERMIA FOR BRAIN-TUMOR USING FERROMAGNETIC IMPLANT WITH LOW CURIE-TEMPERATURE .1. EXPERIMENTAL-STUDY

MAGNETIC INDUCTION HYPERTHERMIA FOR BRAIN-TUMOR USING FERROMAGNETIC IMPLANT WITH LOW CURIE-TEMPERATURE .1. EXPERIMENTAL-STUDY
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DOI:
10.1007/bf00165380
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发表时间:
1986-01-01
影响因子:
3.9
通讯作者:
AMEMIYA, Y
AMEMIYA, Y
中科院分区:
医学2区
文献类型:
--
作者:
KOBAYASHI, T;KIDA, Y;AMEMIYA, Y

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采用低居里温度的铁磁植入体对脑肿瘤进行了磁感应热疗的实验研究。Thermoseed(植入物)由镍-钯合金制成,其被证实通过涡流产生足够的热量,并且还具有在43 ° C之间的低居里点。C-58.degree. C.利用该植入式加热系统,研究了高温对正常大鼠脑组织和脑胶质瘤(T9)的影响。肿瘤组织中来自种子的热传导是正常脑中的两倍。还发现,通过45度的单次局部高温,皮内脑肿瘤在4周内完全消失。C反应60 min。
Experimental study was made on magnetic induction hyperthermia for brain tumor using ferromagnetic implant with low Curie temperature. Thermoseed (implant) was made of nickel-palladium alloy, which was confirmed to produce enough heat by eddy current and also to have low Curie point between 43.degree. C-58.degree. C. Using this implant heating system, the effect of hyperthermia on normal rat brain and intracutaneously innoculated rat gliosarcoma (T9) were studied. Heat conduction from seed was twice as much in tumor tissue as in normal brain. It was also found that the intradermal brain tumors were completely diminished within 4 weeks by single local hyperthermia at 45.degree. C for 60 min.