Long-term use of CPAP therapy for sleep apnea/hypopnea syndrome
Long-term use of CPAP therapy for sleep apnea/hypopnea syndrome
复制标题
DOI：
10.1164/ajrccm.159.4.9807111
复制
发表时间：
1999-04-01
影响因子：
24.7
通讯作者：
Douglas, NJ
中科院分区：
文献类型：
--
作者：
McArdle, N;Devereux, G;Douglas, NJ
经鼻持续气道正压通气（CPAP）治疗的睡眠呼吸暂停低通气综合征（SAHS）患者需要长期使用CPAP以防止症状复发。如果：因此，重要的是要澄清长期CDAP使用的水平和影响长期使用的因素。我们在1986年至1997年接受CPAP试验的1，211例SAHS患者中研究了客观CPAP使用的决定因素，其中1，155例（95.4%）获得了前瞻性CPAP使用数据，中位随访时间为22个月（四分位距[IQR]，12至36个月）。52名（4.5%）患者拒绝CPAP治疗（其中女性和当前吸烟者较多）; 1，103名患者将CPAP带回家，在随访期间，20%的患者停止了治疗，主要是因为缺乏益处。生存分析的方法表明，68%的患者在5年内继续治疗。长期使用CPAP的独立预测因素是打鼾史、呼吸暂停/低通气指数（AHI）和埃普沃思评分; 86%的埃普沃思> 10且AHI大于或等于30的患者在3年时仍在使用CPAP。前3个月内平均每晚使用CPAP强烈预测长期使用。我们的结论是，长期使用CPAP与疾病严重程度和主观嗜睡有关，并且可以在3个月内预测。
patients with the sleep apnea/hypopnea syndrome (SAHS) treated by nasal continuous positive airway pressure (CPAP) need to use CPAP long-term to prevent recurrence of symptoms. If: is thus important to clarify the level of long-term CDAP use and the factors influencing long-term use. We examined determinants of objective CPAP use in 1,211 consecutive patients with SAHS who were prescribed a CPAP trial between 1986 and 1997, prospective CPAP use data were available in 1,155 (95.4%), with a median follow-up of 22 mo (interquartile range [IQR], 12 to 36 mo). Fifty-two (4.5%) patients refused CPAP treatment (these were more often female and current smokers); 1,103 patients took CPAP home, and during follow-up 20% stopped treatment, primarily because of a lack of benefit. Methods of survival analysis showed that 68% of patients continued treatment at 5 yr. Independent predictors of long-term CPAP use were snoring history, apnea/hypopnea index (AHI), and Epworth score; 86% of patients with Epworth > 10 and an AHI greater than or equal to 30 were still using CPAP at 3 yr. Average nightly CPAP use within the first 3 mo was strongly predictive of long-term use. We conclude that long-term CPAP use is related to disease severity and subjective sleepiness and can be predicted within 3 mo.