Different brain structures related to self- and external-agency attribution: a brief review and meta-analysis
Different brain structures related to self- and external-agency attribution: a brief review and meta-analysis
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DOI：
10.1007/s00429-010-0298-1
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发表时间：
2011-06-01
影响因子：
3.1
通讯作者：
Nadel, Jaqueline
中科院分区：
文献类型：
--
作者：
Sperduti, Marco;Delaveau, Pauline;Nadel, Jaqueline
一些神经成像研究一直表明，在探索代理感的任务中，颞顶交界处(TPJ)周围区域被激活。除TPJ外，还报道了不同结构的激活，如背外侧前额叶皮质(DLPFC)、补充前运动区(Pre-SMA)、岛叶和楔前叶。此外，还提出了自我归因和外因归因之间可能的分离。为了检验不同的神经关联对自我和外部机构归因的假设，基于激活似然估计(ALE)方法，对15项PET和fMRI研究(228名受试者)进行了定量荟萃分析。结果表明，外源性激活包括TPJ、SMA前、楔前叶和背内侧前额叶皮质(DMPFC)，而岛叶的激活与自我激活有关。我们讨论了这些发现，强调了岛的作用，并呼吁使用另一种范式，如故意约束和互动模仿来研究代理。
Several neuroimaging studies have consistently shown activations of areas surrounding the temporo-parietal junction (TPJ) during tasks exploring the sense of agency. Beyond TPJ, activations in different structures, such as the dorsolateral prefrontal cortex (dLPFC), the pre-supplementary motor area (pre-SMA), the insula and the precuneus have been reported. Moreover, a possible dissociation between self- and external-agency attribution has been suggested. To test the hypothesis of distinct neural correlates for self- and external-agency attribution a quantitative meta-analysis, based on activation likelihood estimation (ALE) method, across 15 PET and fMRI studies (228 subjects) was conducted. Results show converging activations including the TPJ, pre-SMA, precuneus and dorsomedial prefrontal cortex (dMPFC) in external-agency, while insula activation was related to self-agency. We discuss these findings, highlighting the role of the insula, and calling for the use of alternative paradigms such as intentional binding and interactive imitation to study agency.