WEIGHTED CRITERIA FOR THE DIAGNOSIS OF SYSTEMIC LUPUS-ERYTHEMATOSUS
WEIGHTED CRITERIA FOR THE DIAGNOSIS OF SYSTEMIC LUPUS-ERYTHEMATOSUS
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DOI：
10.1001/archinte.144.2.281
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发表时间：
1984-01-01
影响因子：
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通讯作者：
WILLIAMS, GW
中科院分区：
文献类型：
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作者：
CLOUGH, JD;ELRAZAK, M;WILLIAMS, GW
对87例系统性红斑狼疮（SLE）患者和73例非系统性红斑狼疮（SLE）患者进行了美国风湿病协会（ARA）系统性红斑狼疮（SLE）初步分类标准的敏感性和特异性评价。使用这些数据，贝叶斯定理被用来衡量标准，以便可以开发一个评分系统，允许更准确地使用诊断标准。以类似的方式评估血清学检测结果的组合。加权评分与标准计数的比较显示，无论是1971年或1982年修订的ARA标准，前者的敏感性和特异性更高。加权标准可能更有助于明确界定SLE研究的患者人群。
The preliminary American Rheumatism Association (ARA) criteria for classification of systemic lupus erythematosus (SLE) were evaluated for sensitivity and specificity in 87 patients with SLE and 73 without SLE from a rheumatology population. Using these data, Bayes'' theorem was employed to weight the criteria so that a scoring system could be developed, allowing more accurate use of the criteria in diagnosis. Combinations of serologic test results were evaluated in a similar manner. Comparison of weighted scores with criteria counts showed greater sensitivity and specificity of the former whether the 1971 or modified 1982 ARA criteria were used. Weighted criteria may be more useful in clearly defining patient populations for studies of SLE.