Threat-induced cortical processing and startle potentiation

Threat-induced cortical processing and startle potentiation
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DOI:
10.1097/00001756-200201210-00031
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发表时间:
2002-01-21
期刊:
影响因子:
1.7
通讯作者:
Verbaten, MN
Verbaten, MN
中科院分区:
医学4区
文献类型:
--
作者:
Baas, JMP;Kenemans, JL;Verbaten, MN

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本文介绍了指令恐惧范式中事件相关电位(ERP)所反映的大脑皮层反应。预测休克的安全线索和威胁线索以前所未有的速度呈现(S的平均SOA值为2.1%)。惊吓和主观测量证实,相对于安全线索的威胁会引发恐惧。预测并证实了恐惧加工的几个事件相关事件相关因素:外源性感觉成分的调制、正面选择的正性和P3的增加。此外,还观察到额部负慢波。这些结果将从注意选择模型和情绪处理两方面进行讨论。《神经报告》13:133-137(C)2002里平科特·威廉姆斯·威尔金斯。
This paper presents cortical responses as reflected in event-related potentials (ERP) in an instructed fear paradigm. Safe cues and threat cues that predict shock were presented at an unprecedented fast rate (mean SOA of 2.1 s). Startle and subjective measures confirmed that threat relative to safe cues elicited fear. Several ERP correlates of fear processing were predicted and confirmed: modulation of exogenous sensory components, frontal selection positivity, and increase of P3. Furthermore, a frontal negative slow wave was observed. These results are discussed in relation to attentional selection models and emotional processing. NeuroReport 13:133-137 (C) 2002 Lippincott Williams Wilkins.