A NEW THEORY OF SECONDARY NON-DISJUNCTION IN FEMALE DROSOPHILA-MELANOGASTER
A NEW THEORY OF SECONDARY NON-DISJUNCTION IN FEMALE DROSOPHILA-MELANOGASTER
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DOI：
10.1073/pnas.34.5.179
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发表时间：
1948-01-01
影响因子：
11.1
通讯作者：
COOPER, KW
中科院分区：
文献类型：
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作者：
COOPER, KW
新理论断言，这一过程实际上是由XYX三价体强加的非随机分离。假设Y的每条臂与不同的x染色体配对，形成三价染色体，通常在减数分裂中期以交替模式定向。因此，细胞学特征被设想为类似于D. miranda精子发生中X1YX2三价体的定向分离。先前已知的事实，以及基因专家的结果。设计来测试的方案，似乎完全符合这一解释。
The new theory asserts that the process is actually a case of imposed non-random segregation from an XYX trivalent. Each arm of Y is assumed to pair with a different X-chromosome to form a trivalent which usually orients in alternate pattern at 1st meiotic metaphase. Thus the cytological features are envisioned as similar to the directed segregation from X1YX2 trivalents in the spermatogenesis of D. miranda. Previously known facts, as well as results of genetic expts. designed to test the scheme, appear to be in full accord with this interpretation.