Body mass index in endometriosis

Body mass index in endometriosis
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DOI:
10.1016/j.ejogrb.2004.11.019
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发表时间:
2005-07-01
期刊:
EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY
影响因子:
--
通讯作者:
Ragni, N
Ragni, N
中科院分区:
其他
文献类型:
--
作者:
Ferrero, S;Anserini, P;Ragni, N

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目的:以往的研究并没有建立子宫内膜异位症的存在与体重指数(BMI)之间的明确相关性。研究设计:将366名患有子宫内膜异位症的女性的BMI与248名因妇科良性疾病而接受腹腔镜检查的对照组的BMI进行比较。通过协方差分析(ANCOVA)来控制潜在的混杂变量,证实了单因素分析的显著差异。结果:子宫内膜异位症患者的BMI明显低于对照组(p < 0.001);当分析仅限于BMI正常(18.50-24.99 kg/m(2))的受试者时,证实了这一差异(p = 0.002)。4.8%的对照组和没有子宫内膜异位症的女性肥胖。轻度子宫内膜异位症(修订后的美国生育学会分类,rAFS I-II)和重度子宫内膜异位症(rAFS III-IV)妇女的BMI无显著差异。结论:与对照组相比,子宫内膜异位症患者BMI指数较低,肥胖发生率较低。进一步的研究应探讨子宫内膜异位症患者BMI下降的生理病理基础。2004爱思唯尔爱尔兰有限公司版权所有。
Objective: Previous studies did not establish a clear correlation between the presence of endometriosis and the values of body mass index (BMI).Study design: The BMI of 366 women with endometriosis was compared to that of 248 controls undergoing laparoscopy because of benign gynaecological conditions. Significant differences at univariate analyses were confirmed by using Analysis of covariance (ANCOVA) to control for potential confounding variables.Results: BMI was significantly lower in women with endometriosis than in controls (p < 0.001); this difference was confirmed when the analysis was restricted to subjects with normal BMI (18.50-24.99 kg/m(2)) (p = 0.002). 4.8% of control subjects and no woman with endometriosis were obese. No significant difference was observed in the BMI of women with mild (revised classification of the American Fertility Society, rAFS I-II) and severe endometriosis (rAFS III-IV).Conclusion: Women with endometriosis have lower BMI and are less frequently obese than control subjects. Further studies should investigate the physiopathological basis of decreased BMI in women with endometriosis. (c) 2004 Elsevier Ireland Ltd. All rights reserved.