VASCULAR-DISEASE RISK-FACTORS, URINARY FREE CORTISOL, AND HEALTH HISTORIES IN OLDER ADULTS - SHYNESS AND GENDER INTERACTIONS

VASCULAR-DISEASE RISK-FACTORS, URINARY FREE CORTISOL, AND HEALTH HISTORIES IN OLDER ADULTS - SHYNESS AND GENDER INTERACTIONS
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DOI:
10.1016/0301-0511(93)90090-u
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发表时间:
1993-01-01
影响因子:
2.6
通讯作者:
MORROW, FD
MORROW, FD
中科院分区:
医学3区
文献类型:
--
作者:
BELL, IR;MARTINO, GM;MORROW, FD

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我们研究了害羞和健康之间的关系,在健康筛查调查的老年人(年龄50-88)生活在一个活跃的退休社区在美国西南部(n = 232)。与之前对婴儿的研究一样,患有花粉症、失眠和便秘的老年人比没有这些问题的人更害羞。害羞的人总体上表现出较高的坐位收缩压和站立时立位收缩压的较大幅度下降;害羞的男性比低害羞的男性有更高的高血压史患病率。害羞的男女受试者的高密度脂蛋白胆固醇较低,甘油三酯高于低害羞的受试者;害羞的女性往往比低害羞的女性有更高的低密度脂蛋白胆固醇。相反,研究结果的唾液皮质醇升高,在极度抑制儿童的性别,只有害羞的妇女有较高的24小时尿游离皮质醇排泄比低害羞的妇女,男性表现出相反的模式,可能与抑制侵略。害羞的男性也倾向于报告甲状腺疾病史的患病率高于低害羞的男性(20%对6%)。值得注意的是,自身免疫性甲状腺炎以前与恐慌和抑郁有关,这些疾病反过来又与害羞有关。结合以前在害羞儿童及其家庭中的研究,这些数据提高了以下可能性:(a)动脉血管疾病风险增加;(B)某些害羞老年人肾上腺和/或甲状腺相关疾病风险增加。
We studied relationships between shyness and health during a health screening survey of older adults (ages 50-88) living in an active retirement community in the southwestern United States (n = 232). As in previous studies of infants, older individuals with hay fever, insomnia and constipation were more shy than those without these problems. Shy persons overall showed higher sitting systolic blood pressure and a larger fall in orthostatic systolic blood pressure on standing; shy men had a greater prevalence of hypertension histories than did low-shy men. Shy subjects of both sexes had lower HDL cholesterol and higher triglycerides than did low-shy subjects; shy women tended to have higher LDL cholesterol than did low-shy women. In contrast with findings of elevated salivary cortisol in extremely inhibited children of both sexes, only shy women had higher 24 h urinary free cortisol excretion than did low-shy women; men showed the opposite pattern, possibly related to suppression of aggression. Shy men also tended to report a higher prevalence of thyroid disease history than did low-shy men (20% versus 6%). Notably, autoimmune thyroiditis has previously been linked with panic and depression, disorders which in turn have been associated with shyness. Taken together with previous work in shy children and their families, the data raise the possibility of (a) increased risk for arteriosclerotic vascular disease; and (b) increased risk of adrenal- and/or thyroid-related diseases in certain shy older adults.