Toxicity of chloroform.
Toxicity of chloroform.
复制标题
氯仿的毒性。
作者：
C. Olima;F. Pablo;Richard P. Lim
(1)氯仿通过肺部、口服和皮肤途径被强烈吸收。(2)它对心脏、肝脏、肾脏、皮肤、神经和眼科有不良影响。发生了与使用氯仿有关的死亡事件。在动物中，氯仿具有致癌性和胚胎毒性。(3)自1997年以来，欧洲和法国的药品机构不再认为氯仿是一种简单的溶剂。在药物制剂中仅允许最低量（不超过0.6 mg/天）。
(1) Chloroform is strongly absorbed by the pulmonary, oral and cutaneous routes. (2) It has adverse cardiac, hepatic, renal, dermatological, neurological and ophthalmological effects. Deaths related to chloroform use have occurred. In animals, chloroform is carcinogenic and embryotoxic. (3) Since 1997, the European and French medicines agencies have no longer considered chloroform to be a simple solvent. Only minimal amounts are authorised in drug preparations (no more than 0.6 mg/day).