Dermatofibroma occurring within a tattoo: report of two cases

Dermatofibroma occurring within a tattoo: report of two cases
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纹身内发生的皮肤纤维瘤:两例报告

DOI:
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发表时间:
2008
影响因子:
1.7
通讯作者:
L. Pinquier
L. Pinquier
中科院分区:
医学4区
文献类型:
--
作者:
N. Kluger;H. Cotten;Catherine Magana;L. Pinquier

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To the Editor, The introduction of exogenous pigments into the dermis during tattooing may trigger cutaneous reactions with various histological patterns, including mainly lichenoid, granulomatous, sarcoidosislike, pseudolymphomatous and eczematous reactions. Benign and malignant tumors, such as seborrheic keratosis, pseudo-epitheliomatous hyperplasia, keratoacanthoma, melanoma, basal cell carcinoma and squamous cell carcinoma, may arise in tattoos. Dermatofibroma (DF) is a common benign soft tissue tumor of the skin that affects mainly the lower extremities of young adults. It is considered by some authors to be a reactive or post-inflammatory process and may occur after a trauma. To date, only one case of DF after tattooing has been reported. We report two new cases and discuss a potential link between these two conditions. A 37-year-old man presented for a single hard nodule that had developed several months after a tattoo was applied to the right leg. The tattoo had been performed a year ago in a professional parlor with no immediate complications. His past medical history was notable for seborrheic dermatitis and acne. Physical examination showed a round asymptomatic hard nodule adhering firmly to the overlying epidermis. The lesion measured approximately 6 3 3 mm. The examination was otherwise unremarkable, with no local infection or regional lymph node infection noted. Histology of a full-thickness excision was performed for diagnosis and one treatmentplanning. Examination of the histological sections, stained with hematoxylin and eosin, showed a nodular proliferation in the dermis with a predominance of collagen and fibroblast-like cells in an irregular arrangement without cytological atypia. The overlying epidermis displayed acanthosis without basal hyperpigmentation. In addition, extracellular deposits of black ink-related exogenous pigments were observed, particularly within the proliferation (Fig. 1). A 32-year-old man sought medical attention for a dusky brown lesion located within a tattoo on the left arm. The patient recalled clearly that the skin had been free of any lesion before tattooing. At presentation, the nodule was asymptomatic and