Effects of incomplete pulmonary gas exchange on VO2 max.
Effects of incomplete pulmonary gas exchange on VO2 max.
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不完全肺气体交换对最大摄氧量的影响。
DOI：
10.1152/jappl.1989.66.6.2491
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发表时间：
1989
期刊：
影响因子：
--
通讯作者：
Landry,G
中科院分区：
文献类型：
--
作者：
Powers,SK;Lawler,J;Dempsey,JA;Dodd,S;Landry,G
最近的证据表明，在一些训练有素的耐力运动员中，剧烈运动可能会使血红蛋白结合氧的百分比（%SaO2）降低大于或等于静息值的5%。我们检验了这样一个假设，即肺气体交换限制可能会限制训练有素的运动员表现出运动引起的低氧血症的最大摄氧量。20名健康男性志愿者根据他们的体能状态和运动引起的%SaO2降低小于或等于92%的证明分为两组：1）训练（T），平均VO 2 max = 56.5 ml.kg-1.min-1（n = 13）和2）高度训练（HT），最大运动%SaO2 ≤ 92%，平均VO 2 max = 70.1 ml·kg-1·min-1（n = 7）。受试者进行了两个增量式自行车测力计运动试验，以确定在海平面下常氧（21%O2）和轻度高氧条件下（26%O2）的最大摄氧量。高氧组（94.1 vs. 96.1%）和HT组（90.6 vs. 95.9%）最大运动时的平均%SaO2显著高于常氧组（P <0.05）。与常氧组相比，HT组在高氧期间的平均VO 2 max显著升高（P <0.05）（74.7 vs. 70.1 ml.kg-1.min-1）。相反，在T组中，治疗组之间的VO 2 max（56.5 vs. 57.1 ml.kg-1.min-1）无平均差异（P <0.05）。这些数据表明，肺气体交换可能对在海平面上表现出运动诱导的%SaO2降低的高度训练的运动员的VO 2 max限制有显著贡献。（250字处删节）
Recent evidence suggests that heavy exercise may lower the percentage of O2 bound to hemoglobin (%SaO2) by greater than or equal to 5% below resting values in some highly trained endurance athletes. We tested the hypothesis that pulmonary gas exchange limitations may restrict VO2max in highly trained athletes who exhibit exercise-induced hypoxemia. Twenty healthy male volunteers were divided into two groups according to their physical fitness status and the demonstration of exercise-induced reductions in %SaO2 less than or equal to 92%: 1) trained (T), mean VO2max = 56.5 ml.kg-1.min-1 (n = 13) and 2) highly trained (HT) with maximal exercise %SaO2 less than or equal to 92%, mean VO2max = 70.1 ml.kg-1.min-1 (n = 7). Subjects performed two incremental cycle ergometer exercise tests to determine VO2max at sea level under normoxic (21% O2) and mild hyperoxic conditions (26% O2). Mean %SaO2 during maximal exercise was significantly higher (P less than 0.05) during hyperoxia compared with normoxia in both the T group (94.1 vs. 96.1%) and the HT group (90.6 vs. 95.9%). Mean VO2max was significantly elevated (P less than 0.05) during hyperoxia compared with normoxia in the HT group (74.7 vs. 70.1 ml.kg-1.min-1). In contrast, in the T group, no mean difference (P less than 0.05) existed between treatments in VO2max (56.5 vs. 57.1 ml.kg-1.min-1). These data suggest that pulmonary gas exchange may contribute significantly to the limitation of VO2max in highly trained athletes who exhibit exercise-induced reductions in %SaO2 at sea level.(ABSTRACT TRUNCATED AT 250 WORDS)