Fetal membrane distention: Determination of the intrauterine surface area and distention of the fetal membranes preterm and at term
Fetal membrane distention: Determination of the intrauterine surface area and distention of the fetal membranes preterm and at term
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DOI：
10.1016/s0002-9378(00)70501-1
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发表时间：
2000-01-01
影响因子：
9.8
通讯作者：
Bryant-Greenwood, G
中科院分区：
文献类型：
--
作者：
Millar, LK;Stollberg, J;Bryant-Greenwood, G
目的：准确测量早产儿和足月儿宫内表面积和胎膜膨胀度。研究设计：对23例妊娠25~41周的孕妇子宫进行连续纵向成像。数学(Wolfram Research，Inc.，Champaign，III)程序组装了一个三维图像，并计算了每个患者的宫内表面积。产后在体外测量胎盘羊膜和胎膜表面积。结果：平均计算的宫内表面积分别为1037+/-70 cm(2)(孕25~29周，n=4)、1376+/-121 cm(2)(孕30~34周，n=4)和1876+/-307 cm(2)(孕37~41周，n=15，P=0.0021)。胎龄25~29周、30~34周和37~41周的排膜表面积分别为737±61 cm(2)、855±77 cm(2)和1115±149 cm(2)。25~29周4例，30~34周1.6+/-0.2，足月1.7+/-0.3例。结论：妊娠25~29周，宫腔表面积与排膜面积之比为1.4+/-0.05；体外测量的胎膜表面积增加的程度较小。因此，胎膜在体内会膨胀。
OBJECTIVE: This study was undertaken to obtain an accurate measurement of the intrauterine surface area and the degree of distention of the apposed fetal membranes preterm and at term.STUDY DESIGN: Serial longitudinal images of the uterus in 23 women between 25 and 41 weeks' gestation were obtained by ultrasonography. A Mathematica (Wolfram Research, Inc, Champaign, III) program assembled a 3-dimensional image and calculated the intrauterine surface area for each patient. The surface areas of the placental amnion and membranes were measured in vitro after delivery. From these measurements the degree of distention of each fetal membrane in vivo was calculated.RESULTS: The mean calculated intrauterine surface areas were as follows: 1037 +/- 70 cm(2) (25-29 weeks' gestation, n = 4), 1376 +/- 121 cm(2) (30-34 weeks' gestation, n = 4), and 1876 +/- 307 cm(2) (37-41 weeks' gestation, n = 15, P = .0021 by Wilcoxon rank sum test). The surface areas of the expelled membranes at 25 to 29, 30 to 34, and 37 to 41 weeks' gestation were 737 +/- 61 cm(2), 855 +/- 77 cm(2), and 1115 +/- 149 cm(2), respectively. The ratios of intrauterine surface area to the area of the expelled membrane and hence a measure of the degree of distention in vivo were 1.4 +/- 0.05 at 25 to 29 weeks' gestation (n = 4), 1.6 +/- 0.2 at 30 to 34 weeks' gestation (n = 4), and 1.7 +/- 0.3 at term (n = 15).CONCLUSION: The intrauterine surface area in vivo increases during gestation. The surface area of the fetal membranes as measured in vitro increases to a lesser extent. The fetal membranes are therefore distended in vivo.