In situ synthesis of porous silica nanoparticles for covalent immobilization of enzymes.
In situ synthesis of porous silica nanoparticles for covalent immobilization of enzymes.
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DOI：
10.1039/c1nr11153a
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发表时间：
2012-01
期刊：
影响因子：
6.7
通讯作者：
Xiaowei Yang;Zhengwei Cai;Zhangmei Ye;Sheng Chen;Yu Yang;Haifang Wang;Yuanfang Liu;Aoneng Cao
中科院分区：
文献类型：
--
作者：
Xiaowei Yang;Zhengwei Cai;Zhangmei Ye;Sheng Chen;Yu Yang;Haifang Wang;Yuanfang Liu;Aoneng Cao
一种简单的方法是用来共价包封酶在二氧化硅纳米粒子。高酶载量和多孔通道突出了包封作用，这些通道为小底物和产物分子提供有效扩散，同时防止蛋白酶降解。
A simple method is used to covalently encapsulate enzymes in silica nanoparticles. The encapsulation is highlighted by the high enzyme loading and porous channels that provide efficient diffusion for small substrate and product molecules while preventing protease degradation.