MovieMaker: a web server for rapid rendering of protein motions and interactions
MovieMaker: a web server for rapid rendering of protein motions and interactions
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DOI：
10.1093/nar/gki485
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发表时间：
2005-07-01
影响因子：
14.9
通讯作者：
Wishart, DS
中科院分区：
文献类型：
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作者：
Maiti, R;Van Domselaar, GH;Wishart, DS
MovieMaker是一个Web服务器，允许生成短（类似于10秒），可下载的蛋白质运动电影。它接受PDB文件或PDB登录号作为输入，并自动计算、渲染和合并必要的图像文件，以创建涵盖广泛蛋白质运动和其他动态过程的彩色动画。用户可以选择动画（i）简单的旋转，（ii）两个终态构象之间的变形，（iii）短尺度，皮秒振动，（iv）配体对接，（v）蛋白质寡聚化，（vi）中等尺度纳秒（系综）运动和（vii）蛋白质折叠/展开。MovieMaker不执行分子动力学计算。相反，它是一个动画工具，使用复杂的叠加算法结合笛卡尔坐标插值来快速自动计算许多动画所需的中间结构。用户可以广泛控制渲染风格、结构颜色、动画质量、背景和其他图像功能。MovieMaker旨在成为一个通用服务器，允许专家和非专家轻松生成有用的，信息丰富的蛋白质动画，用于教育和说明目的。MovieMaker可在http://wishart.biology.ualberta.ca/moviemaker上访问。
MovieMaker is a web server that allows short (similar to 10 s), downloadable movies of protein motions to be generated. It accepts PDB files or PDB accession numbers as input and automatically calculates, renders and merges the necessary image files to create colourful animations covering a wide range of protein motions and other dynamic processes. Users have the option of animating (i) simple rotation, (ii) morphing between two end-state conformers, (iii) short-scale, picosecond vibrations, (iv) ligand docking, (v) protein oligomerization, (vi) mid-scale nanosecond (ensemble) motions and (vii) protein folding/unfolding. MovieMaker does not perform molecular dynamics calculations. Instead it is an animation tool that uses a sophisticated superpositioning algorithm in conjunction with Cartesian coordinate interpolation to rapidly and automatically calculate the intermediate structures needed for many of its animations. Users have extensive control over the rendering style, structure colour, animation quality, background and other image features. MovieMaker is intended to be a general-purpose server that allows both experts and non-experts to easily generate useful, informative protein animations for educational and illustrative purposes. MovieMaker is accessible at http://wishart.biology.ualberta.ca/moviemaker.