The first kidney transplantation after recipient and living donor recovered from COVID-19.

The first kidney transplantation after recipient and living donor recovered from COVID-19.
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DOI:
10.14744/nci.2021.70457
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发表时间:
2021
影响因子:
1
通讯作者:
Ersoy Yesil E
Ersoy Yesil E
中科院分区:
其他
文献类型:
--
作者:
Kucuk EV;Sit D;Kayabasi H;Tahra A;Sobay R;Yilmaz SNG;Karaoglu C;Ersoy Yesil E

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SARS-CoV-2仍然是对世界的重大威胁。在这次大流行中,全世界的移植活动在很大程度上受到了影响。我们仍然面临这一流行病;然而,经过规定,我们已经开始了移植活动。我们报道首例受体和活体供体从COVID-19中恢复的肾移植。一例31岁男性肾功能衰竭患者与abo血型相容的亲属一起接受移植。移植前对受体和供体进行COVID-19检测,聚合酶链反应均为阳性。患者症状轻微,接受治疗;活体供体也接受了治疗。康复后30天,手术成功。术后15天,患者使用霉酚酸酯(MMF)、他克莫司和类固醇出院。在手术后45天的随访中,他们的COVID-19都呈阴性。虽然缺乏关于安全性和短期随访的文献,但对于COVID-19康复的患者,经过仔细选择并注意注意事项后,可以考虑活体供体移植。
SARS-CoV-2 is still a major threat to the world. In this pandemic, transplantation activities have largely been affected worldwide. We are still facing with this pandemic; however, after regulations, we have started our transplantation activities. We report the first kidney transplantation whose recipient and living donor recovered from COVID-19. A 31-year-old male with renal failure was admitted for transplantation with an ABO-compatible relative. The recipient and the donor were tested for COVID-19 before transplantation, and they were both positive with a polymerase chain reaction. The recipient had minor symptoms and received therapy; the living donor also received therapy. Thirty days after recovery, surgery was performed successfully. The recipient was discharged with mycophenolate mofetil (MMF), tacrolimus, and steroid 15 days after surgery. In the follow-up, they were both negative for COVID-19 45 days after surgery. Although there is missing literature regarding safety concerns and short-term follow-up, living-donor transplantation may be considered for patients, who recovered from COVID-19, after careful selection with paying attention to precautions.
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