The Clock Reading Test: validation of an instrument for the diagnosis of dementia and disorders of visuo-spatial cognition

The Clock Reading Test: validation of an instrument for the diagnosis of dementia and disorders of visuo-spatial cognition
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DOI:
10.1017/s104161020600456x
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发表时间:
2007-04-01
影响因子:
7
通讯作者:
Olbrich, Susanne
Olbrich, Susanne
中科院分区:
医学1区
文献类型:
--
作者:
Schmidtke, Klaus;Olbrich, Susanne

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背景:由12个项目组成的时钟阅读测试(CRT)可以对时钟阅读能力进行精细评分。它非常注重视觉-空间处理,不需要执行处理。方法:对200例痴呆组、105例轻度认知障碍组、20例局灶性顶叶病变组和老年对照组进行CRT检查。结果:CRT对阿尔茨海默病、阿尔茨海默病、混合性痴呆和路易体痴呆患者的认知功能损害具有较高的信度和敏感性。正常受试者和MCI、额颞叶痴呆或脑小血管病患者的脑功能损害很小或无损害。结论:CRT和CDT是不同需求类型的时钟加工测验。它们在痴呆和视空间障碍的神经心理学诊断中可以相辅相成。
Background: The 12-item Clock Reading Test (CRT) allows a fine-graded assessment of clock-reading ability. It has a strong focus on visuo-spatial processing and requires no executive processing. This study evaluated the reliability, validity, sensitivity and specificity of the CRT for the diagnosis of dementia and visuo-spatial dysfunction.Methods: The CRT, the Clock Drawing Test (CDT) and other tests were applied to groups of 200 subjects with dementia, 105 subjects with mild cognitive impairment (MCI), 20 subjects with focal parietal lesions and 64 elderly control subjects.Results: The CRT was found to be reliable and sensitive for the detection of cognitive impairment in parietal lesions, Alzheimer-, mixed- and Lewy Body dementia. Normal subjects and patients with MCI, frontotemporal dementia or cerebral small vessel disease showed little or no impairment.Conclusion: CRT and CDT are clock-processing tests with different demand profiles. They can supplement each other in the neuropsychological diagnosis of dementia and visuo-spatial dysfunction.