Sarcopenia Screened With SARC-F Questionnaire Is Associated With Quality of Life and 4-Year Mortality
Sarcopenia Screened With SARC-F Questionnaire Is Associated With Quality of Life and 4-Year Mortality
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DOI：
10.1016/j.jamda.2016.07.029
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发表时间：
2016-12-01
影响因子：
7.6
通讯作者：
Yang, Rong-Sen
中科院分区：
文献类型：
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作者：
Wu, Tai-Yin;Liaw, Chen-Kun;Yang, Rong-Sen
目的：肌少症的诊断没有金标准。我们的目的是评估使用SARC-F（行动迟缓、行走辅助、从椅子上站起来、爬楼梯、跌倒）筛查肌肉减少症的有效性。设计：前瞻性队列研究。地点：台湾社区医院。参与者：居住在社区的长者。测量方法：每年对参与者进行结构化问卷调查。问卷项目被重新编码为SARC-F的5个项目（行动迟缓、辅助行走、起身、爬楼梯、跌倒）。在基准年，测试了一个亚组的握力和身体成分。医疗保健利用和死亡率基于自我报告和医院记录。我们的主要结局是4年死亡率。次要结局包括住院、急诊护理使用和使用CASP-12量表测量的生活质量(控制、自主、自我实现、快乐（控制、自主、自我实现、压力）。结果：共670名受试者。平均年龄76.1岁（标准差6.36）。其中一半为男性（n = 340, 50.7%）。肌肉减少症的患病率为6.1% （n = 41）。SARC-F评分与握力（P = .001）和骨骼肌组成（P = .045）呈负相关。肌肉减少症患者多为女性（P = 0.005）和老年人（P < 0.001）。在单变量分析中，肌肉减少症与1- 4年死亡率相关(P = 0.033, 0.001, 0.001，
Objectives: There is no gold standard in diagnosing sarcopenia. We aimed to assess the validity of screening sarcopenia using SARC-F (sluggishness, assistance in walking, rise from a chair, climb stairs, falls).Design: Prospective cohort study.Setting: Community hospital in Taiwan.Participants: Community-dwelling senior citizens.Measurements: Participants were interviewed with a structured questionnaire annually. The questionnaire items were recoded into the 5 items of SARC-F (sluggishness, assistance in walking, rise from a chair, climb stairs, falls). In the baseline year, a subgroup was tested for grip strength and body composition. Healthcare utilization and mortality were based on self-report and hospital records. Our main outcome was 4-year mortality. Secondary outcomes included hospitalization, emergency care use, and quality of life (QOL) measured using the CASP-12 scale (control, autonomy, self-realization, pleasure (control, autonomy, self-realization, pressure).Results: There were 670 participants. The mean age was 76.1 (standard deviation 6.36). One-half were men (n = 340, 50.7%). The prevalence of sarcopenia was 6.1% (n = 41). SARC-F scores were inversely associated with grip strength (P = .001) and skeletal muscle composition (P = .045). Participants with sarcopenia were mostly women (P = .005) and older (P < .001). In univariate analysis, sarcopenia was associated with 1- to 4-year mortalities (P = .033,.001,.001,