Association between infertility treatment and symptoms of postpartum depression

Association between infertility treatment and symptoms of postpartum depression
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DOI:
10.1016/j.fertnstert.2014.07.1247
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发表时间:
2014-11-01
影响因子:
6.7
通讯作者:
Prasad, Mona R.
Prasad, Mona R.
中科院分区:
医学2区
文献类型:
--
作者:
Lynch, Courtney D.;Prasad, Mona R.

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目的:研究不孕症治疗与产后抑郁症后续症状之间的关系。设计:横断面研究。设置:不适用。患者:2009- 2010年分娩活产婴儿的妇女。干预:无。主要结果测量:产后抑郁症症状的几率。结果:数据来自疾病控制和预防中心的妊娠风险评估监测系统(PRAMS)。16个州的不孕症治疗数据可用,其中母亲在分娩后2至4个月进行抽样,以完成标准化PRAMS问卷。不孕症治疗状态与出生证明上报告的一致。通过母亲问卷获得母亲的心理健康状况。在Stata 12.0中使用样本权重分析数据,以产生基于人群的估计值。在收集不孕症治疗数据的42,614名妇女中,2,277名(5.3%)妇女的不孕症治疗状态缺失。在40,337名符合条件的女性中,12.9%的人表示感到沮丧,沮丧或悲伤,6.0%的人表示感到绝望。这些妇女被认为有产后抑郁症的症状。即使在调整混杂因素后,不孕症治疗状况与产后抑郁症状之间也没有独立的联系。相比之下,有一个孩子住进新生儿重症监护室,吸烟,在分娩前12个月内经历了更多的压力源,以及有孕前心理健康护理史与产后抑郁症状的几率增加有关。结论:在一项基于人群的美国妇女样本中,在不孕症治疗的帮助下怀孕并没有增加产后抑郁症状的几率。(C)2014年,美国生殖医学会(American Society for Reproductive Medicine)
Objective: To examine the association between infertility treatment and subsequent symptoms of postpartum depression.Design: Cross-sectional study.Setting: Not applicable.Patient(s): Women who delivered live-born infants from 2009-2010.Intervention(s): None.Main Outcome Measure(s): Odds of symptoms of postpartum depression.Result(s): Data were obtained from the Center for Disease Control and Prevention's Pregnancy Risk Assessment Monitoring System (PRAMS). Data on infertility treatment were available for 16 states in which mothers were sampled 2 to 4 months after delivery to complete the standardized PRAMS questionnaire. Infertility treatment status was as reported on the birth certificate. Maternal mental health was obtained via the maternal questionnaire. Data were analyzed in Stata 12.0 with sample weights to produce population-based estimates. Among the 42,614 women who resided in states in which infertility treatment data were collected, infertility treatment status was missing for 2,277 (5.3%) women. Among the 40,337 eligible women, 12.9% reported feeling down, depressed or sad, and 6.0% reported feeling hopeless. These women were considered to have symptoms of postpartum depression. Even after adjustment for confounders, there was no independent association between infertility treatment status and symptoms of postpartum depression. In contrast, having a child admitted to neonatal intensive care, smoking, experiencing a higher number of stressors in the 12 months before delivery, and a history of having prepregnancy mental health care were associated with an increased odds of having symptoms of postpartum depression.Conclusion(s): In a population-based sample of U.S. women, conceiving with the help of infertility treatment did not increase the odds of experiencing symptoms of postpartum depression. (C) 2014 by American Society for Reproductive Medicine.