Classification, epidemiology, and natural history of fibromyalgia.

Classification, epidemiology, and natural history of fibromyalgia.
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DOI:
10.1007/s11916-001-0021-2
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发表时间:
2001-08-01
影响因子:
3.7
通讯作者:
Harth, M
Harth, M
中科院分区:
医学3区
文献类型:
--
作者:
White, K P;Harth, M

文献摘要

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纤维肌痛 (FM),也称为纤维肌痛综合征 (FMS) 和纤维组织炎,是一种常见的非关节风湿病,与慢性全身肌肉骨骼疼痛、疲劳和一系列其他症状有关。有些人批评将 FM 分类为一个独特的医学实体,但现有数据表明,符合 FM 病例定义的个体在临床上与那些不符合完整 FM 定义的慢性广泛疼痛患者有所不同。临床研究发现 FM 在世界各国都很常见;其中包括专科和普通诊所的研究。一般人群研究也是如此,显示 FM 的患病率在 0.5% 到 5% 之间。关于 FM 风险因素的知识有限。女性面临的风险更大,而且到中年时风险似乎会增加,然后下降。尽管一些作者声称过度慷慨的西方补偿制度助长了 FM 的流行,但没有数据表明 FM 的发病率或患病率正在增加;此外,现有数据驳斥了 FM 患病率与补偿之间的任何关联。现有研究也不支持 FM 标签本身导致疾病行为和增加对医疗系统依赖的说法。本文综述了 FM 的分类、流行病学和自然史。
Fibromyalgia (FM), also known as fibromyalgia syndrome (FMS) and fibrositis, is a common form of nonarticular rheumatism that is associated with chronic generalized musculoskeletal pain, fatigue, and a long list of other complaints. Some have criticized the classification of FM as a distinct medical entity, but existing data suggest that individuals meeting the case definition for FM are clinically somewhat distinct from those with chronic widespread pain who do not meet the full FM definition. Clinic studies have found FM to be common in countries worldwide; these include studies in specialty and general clinics. The same is true of general population studies, which show the prevalence of FM to be between 0.5% and 5%. Knowledge about risk factors for FM is limited. Females are at greater risk, and risk appears to increase through middle age, then decline. Although some authors claim that an epidemic of FM has been fueled by an over-generous Western compensation system, there are no data that demonstrate an increasing incidence or prevalence of FM; moreover, existing data refute any association between FM prevalence and compensation. Claims that the FM label itself causes illness behavior and increased dependence on the medical system also are not supported by existing research. This article reviews the classification, epidemiology, and natural history of FM.