EFFECT OF EPINEPHRINE ON CORNEAL ENDOTHELIUM
EFFECT OF EPINEPHRINE ON CORNEAL ENDOTHELIUM
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DOI：
10.1016/0002-9394(75)90078-1
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发表时间：
1975-01-01
影响因子：
4.2
通讯作者：
HYNDIUK, RA
中科院分区：
文献类型：
--
作者：
HULL, DS;CHEMOTTI, MT;HYNDIUK, RA
眼膜内肾上腺素已被提倡用于治疗眼内手术中虹膜出血和瞳孔扩张不足。商品肾上腺素1:10 00及其防腐剂亚硫酸氢钠对兔、猴眼角膜内皮功能和超微结构造成损伤，亚硫酸氢钠是损伤源。用1:50 0稀释市售肾上腺素在0.1%亚硫酸氢钠或新鲜制备的重酒石酸肾上腺素1:10 0稀释碳酸氢盐林格可预防内皮损伤。
Intracameral epinephrine has been advocated for treatment of iris bleeding and inadequate pupillary dilatation during intraocular surgery. Commercial epinephrine 1: 1000 with its preservative sodium bisulfite damaged corneal endothelial function and ultrastructure in rabbit and monkey eyes with sodium bisulfite the source of the damage. Endothelial damage can be prevented with a 1: 5000 dilution of commercially available epinephrine in 0.1% sodium bisulfite or freshly prepared epinephrine bitartrate 1: 1000 with a bicarbonate Ringers.