Comparative mortality following single whole-body exposures of mice to fission neutrons and Co60 gamma rays.

Comparative mortality following single whole-body exposures of mice to fission neutrons and Co60 gamma rays.
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小鼠单次全身暴露于裂变中子和 Co60 伽马射线后的死亡率比较。

DOI:
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发表时间:
1957
期刊:
影响因子:
19.7
通讯作者:
D. L. Jordan
D. L. Jordan
中科院分区:
医学1区
文献类型:
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作者:
H. Vogel;J. Clark;D. L. Jordan

文献摘要

被引文献

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在过去的几年里,已经计划并进行了实验,以测试快中子和Co60伽马射线在对小鼠的急性致死作用中的放射生物加性[1]。由于高能伽马射线和裂变中子经常相遇,它们在产生某种生物效应时是否相加的问题既有理论意义,也有现实意义。作为这些研究的基础,分别在两种辐射单独暴露后,构建了小鼠的完整剂量-存活曲线。这篇论文的目的是提供这些暴露后30天急性期的生存数据。材料和方法动物:实验所用小鼠为CF1雌性,5~6周龄运往本实验室。每周一到,他们就被分成八人一组,通过随机数字表的方式。每组被安置在一个塑料笼子(2)中,并被隔离放置两到四周,然后被...
During the past several years experiments have been planned and undertaken to test the radiobiological additivity of fast neutrons and Co60 gamma rays in their acute lethal action on mice (1). Since high-energy gamma rays and fission neutrons are often encountered together, the question of whether they are additive in producing certain biological effects has practical as well as theoretical significance. As a basis for these studies, complete dose-survival curves for the mouse were constructed following exposure to each of the two radiations alone. The object of this paper is to present these survival data for the thirty-day acute period following such exposures. Material and Methods Animals: The mice used in these experiments were CF #1 females, shipped to our Laboratories at five to six weeks of age. Upon arrival each week, they were divided into groups of eight, by means of a table of random numbers. Each group was housed in a plastic cage (2) and placed in isolation for two to four weeks before being ...