Enantioselective Synthesis of Planar-Chiral Phosphaferrocenes by Molybdenum-Catalyzed Asymmetric Interannular Ring-Closing Metathesis
Enantioselective Synthesis of Planar-Chiral Phosphaferrocenes by Molybdenum-Catalyzed Asymmetric Interannular Ring-Closing Metathesis
复制标题
DOI：
10.1021/ja910348z
复制
发表时间：
2010-02-24
影响因子：
15
通讯作者：
Takahashi, Tamotsu
中科院分区：
文献类型：
--
作者：
Ogasawara, Masamichi;Watanabe, Susumu;Takahashi, Tamotsu
本文首次利用钼催化的不对称合环复分解（ARCM）在99% ee范围内实现了平面手性磷二茂铁的对映选择性合成，这是ARCM在无立体中心分子中诱导手性的首次应用。
Enantioselective synthesis of planar-chiral phosphaferrocenes was realized for the first time by molybdenum-catalyzed asymmetric ring-closing metathesis (ARCM) in up to 99% ee, which is the first application of ARCM to induction of chirality in molecules devoid of stereogenic centers.