PESTICIDE EXPOSURES, CHOLINESTERASE DEPRESSION, AND SYMPTOMS AMONG NORTH-CAROLINA MIGRANT FARMWORKERS
PESTICIDE EXPOSURES, CHOLINESTERASE DEPRESSION, AND SYMPTOMS AMONG NORTH-CAROLINA MIGRANT FARMWORKERS
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DOI：
10.2105/ajph.84.3.446
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发表时间：
1994-03-01
影响因子：
12.7
通讯作者：
AUER, A
中科院分区：
文献类型：
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作者：
CIESIELSKI, S;LOOMIS, DP;AUER, A
目标.我们对农场工人和非农场工人的红细胞胆碱酯酶水平、农药暴露和健康影响进行了一项基于临床的研究，以确定暴露风险和相关发病率。方法。在两个社区卫生中心依次招募了202名农场工人和42名非农场工人。用比色法测定红细胞胆碱酯酶水平。调查人员获得了人口统计学、职业史、暴露和暴露的数据。农场工人的胆碱酯酶水平（30.28 U/g血红蛋白）显著低于非农场工人（32.3 U/g血红蛋白）。12%的农场工人，但没有非农场工人，水平很低。施用杀虫剂的农场工人的胆碱酯酶水平也较低。一半的农场工人报告说，他们被喷洒了杀虫剂，在有明显化学气味的田地里工作。在报告的症状中，只有腹泻与胆碱酯酶水平有关。然而，报告的暴露与乳腺癌密切相关。农场工人报告了许多违反州和联邦法规的农药暴露。农场工人的胆碱酯酶水平显着低于非农场工人，虽然只有喷洒农药与非常低的水平。
Objectives. We conducted a clinic-based study of erythrocyte cholinesterase levels, pesticide exposures, and health effects among farmworkers and non farmworkers to determine risks for exposure and associated morbidity.Methods. Two hundred two farmworkers and 42 nonfarmworkers were recruited sequentially at two community health centers. Erythrocyte cholinesterase levels were measured colorimetrically. Questionnaires obtained data on demographics, occupational history, exposures, and symptoms.Results. Cholinesterase levels were significantly lower among farmworkers (30.28 U/g hemoglobin) than among nonfarmworkers (32.3 U/g hemoglobin). Twelve percent of farmworkers, but no nonfarmworkers, had very low levels. Farmworkers applying pesticides also had lower cholinesterase levels. One half of farmworkers reported being sprayed by pesticides and working in fields with an obvious chemical smell. Of reported symptoms, only diarrhea was associated with cholinesterase levels. Reported exposures, however, were strongly associated with symptoms.Conclusions. Farmworkers reported many pesticide exposures that violate state and federal regulations. Farmworkers had cholinesterase levels significantly lower than those of nonfarmworkers, although only spraying pesticides was associated with very low levels.