CHEMICAL COUPLING OF PEPTIDES AND PROTEINS TO POLYSACCHARIDES BY MEANS OF CYANOGEN HALIDES
CHEMICAL COUPLING OF PEPTIDES AND PROTEINS TO POLYSACCHARIDES BY MEANS OF CYANOGEN HALIDES
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DOI：
10.1038/2141302a0
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发表时间：
1967-01-01
期刊：
影响因子：
64.8
通讯作者：
ERNBACK, S
中科院分区：
文献类型：
--
作者：
AXEN, R;PORATH, J;ERNBACK, S
生物活性蛋白质和多肽可以通过各种方式偶联到纤维素、淀粉和交联多糖凝胶如“Sephadex”上。为此目的使用卤化氰得到高产率的结合多肽或蛋白质，其保留了其活性的实质部分。
Bio-logically active proteins and polypeptides can be coupled by various means to cellulose, starch and cross-linked polysaccharide gels such as "Sephadex". The use of cyanogen halides for this purpose gives a high yield of bound polypeptide or protein which retains a substantial part of its activity.