Determinants of geographic variation in Helicobacter pylori infection among children on the US-Mexico border.
Determinants of geographic variation in Helicobacter pylori infection among children on the US-Mexico border.
复制标题
美国-墨西哥边境儿童幽门螺杆菌感染地理差异的决定因素。
DOI：
10.1093/aje/kwg219
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发表时间：
2003
影响因子：
5
通讯作者：
Day,RSue
中科院分区：
文献类型：
--
作者：
O'Rourke,Kathleen;Goodman,KarenJ;Grazioplene,Mariah;Redlinger,Thomas;Day,RSue
传统上发展中国家的幽门螺杆菌感染率高于发达国家，但这些差异的具体原因尚不完全清楚。H.幽门螺杆菌一般在成人发病，慢性感染通常始于儿童时期。在这项横断面研究（1998-2000）中，作者比较了H。格兰德河两岸6岁以下儿童的幽门螺杆菌感染。参与者包括264名低收入家庭妇女的子女，他们从1998年4月至2000年10月在墨西哥华雷斯或得克萨斯州埃尔帕索的诊所接受服务。通过个人访谈和H.幽门抗体H.与美国儿童相比，墨西哥儿童的幽门螺杆菌患病率为3.94（95%置信区间：1.72，9.06）。调整协变量后，比值比降至1.70（95%置信区间：0.64，4.52）。调整，产生最大的优势比降低的位置是那些家庭拥挤和母亲的教育。这项研究确定了可能解释H地理变异的特定因素。儿童幽门螺杆菌感染率。
Rates ofHelicobacter pyloriinfection are traditionally higher in developing countries than in developed countries, but the specific reasons for these differences are not fully clear. While chronic diseases resulting fromH. pyloriare generally of adult onset, chronic infection usually begins in childhood. In this cross-sectional study (1998–2000), the authors compared prevalences ofH. pyloriinfection among children under age 6 years on both sides of the Rio Grande. Participants included 264 children of women from low-income families who were receiving services at health clinics in Juarez, Mexico, or El Paso, Texas, from April 1998 through October 2000. Data were collected through personal interviews and serologic testing forH. pyloriantibodies. The crude odds ratio forH. pyloriprevalence among Mexican children as compared with US children was 3.94 (95% confidence interval: 1.72, 9.06). After adjustment for covariates, the odds ratio decreased to 1.70 (95% confidence interval: 0.64, 4.52). The adjustments that produced the greatest reduction in the odds ratio for location were those for household crowding and maternal education. This study identified specific factors that may explain geographic variation inH. pyloriprevalence among children.