Covalently bonded adducts of deoxyribonucleic acid (DNA) oligonucleotides with single-wall carbon nanotubes: Synthesis and hybridization
Covalently bonded adducts of deoxyribonucleic acid (DNA) oligonucleotides with single-wall carbon nanotubes: Synthesis and hybridization
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DOI：
10.1021/nl025729f
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发表时间：
2002-12-01
期刊：
影响因子：
10.8
通讯作者：
Hamers, RJ
中科院分区：
文献类型：
--
作者：
Baker, SE;Cai, W;Hamers, RJ
我们开发了一种多步骤方法来形成单壁碳纳米管(SWNT)和环氧核糖核酸(DNA)寡核苷酸的共价连接加合物。用X射线光电子能谱表征了最初的化学修饰，形成了端胺的单壁碳纳米管，然后将其共价连接到DNA上。得到的DNA-SWNT加合物选择性地与互补序列杂交，与非互补序列只有最小的相互作用。
We have developed a multistep route to the formation of covalently linked adducts of single-wall carbon nanotubes (SWNT) and cleoxyribonucleic acid (DNA) oligonucleotides. X-ray photoelectron spectroscopy was used to characterize the initial chemical modification to form amine-terminated SWNTs, which were then covalently linked to DNA. The resulting DNA-SWNT adducts hybridize selectively with complementary sequences, with only minimal interaction with noncomplementary sequences.