Diagnostic efficacy of gadoxetic acid-enhanced MRI for the detection and characterisation of liver metastases: comparison with multidetector-row CT
Diagnostic efficacy of gadoxetic acid-enhanced MRI for the detection and characterisation of liver metastases: comparison with multidetector-row CT
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DOI：
10.1259/bjr/25139667
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发表时间：
2012-05-01
影响因子：
2.6
通讯作者：
Han, Y. M.
中科院分区：
文献类型：
--
作者：
Kim, Y. K.;Park, G.;Han, Y. M.
目的：我们比较了钆塞酸增强 MRI 和 16 排多层 CT (MDCT) 检测肝转移灶以及区分肝转移灶与肝囊肿和血管瘤的能力。方法：67 例患者，其中 110 个肝转移瘤（大小 0.3-2.5 cm）、33 个血管瘤（大小 0.5-1.5 cm） 17 个囊肿（大小 0.3-1.0 cm）接受了 4 期 MDCT 和钆塞酸增强 MRI，包括早期动态期、对比后 T-2 加权涡轮自旋回波序列和 20 分钟肝细胞选择性期。两名观察者以随机顺序独立分析每幅图像。使用受试者操作特征分析计算 MDCT 和钆塞酸增强 MRI 病变检测和鉴别的敏感性和诊断准确性。结果：对于两名观察者，钆塞酸增强 MRI 的 Az 值（平均值 0.982 和 0.981）显着高于 MDCT 的 Az 值（平均值 0.839 和 0.892）（p
Objectives: We compared the diagnostic performance of gadoxetic acid-enhanced MRI and 16-slice multidetector CT (MDCT) with respect to their abilities to detect hepatic metastases and differentiate hepatic metastases from hepatic cysts and haemangiomas.Methods: 67 patients with 110 liver metastases (size 0.3-2.5 cm), 33 haemangiomas (size 0.5-1.5 cm) and 17 cysts (size 0.3-1.0 cm) underwent 4-phase MDCT and gadoxetic acid-enhanced MRI, including early dynamic phases, post-contrast T-2 weighted turbo spin echo sequences and 20 min hepatocyte-selective phases. Two observers independently analysed each image in random order. Sensitivity and diagnostic accuracy for lesion detection and differentiation for MDCT and gadoxetic acid-enhanced MRI were calculated using receiver operating characteristic analysis.Results: For both observers, the Az values of gadoxetic acid-enhanced MRI (mean, 0.982 and 0.981) were significantly higher than the Az values of MDCT (mean, 0.839 and 0.892) (p