Prevalence and correlates of diabetes in national schizophrenia samples
Prevalence and correlates of diabetes in national schizophrenia samples
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DOI：
10.1093/oxfordjournals.schbul.a033504
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发表时间：
2000-01-01
影响因子：
6.6
通讯作者：
Lehman, A
中科院分区：
文献类型：
--
作者：
Dixon, L;Weiden, P;Lehman, A
精神分裂症患者患II型糖尿病的风险可能会增加，因为抗精神病药物的副作用，整体身体健康状况较差，生活方式不健康，医疗保健较差。本研究使用由精神分裂症患者结局研究小组（PORT）收集的数据库来评估接受精神分裂症治疗的大人群中糖尿病的患病率、人口统计学和临床相关性。在精神分裂症港口，医疗补助和医疗保险的数据，从1991年和最近的访谈数据收集有关精神分裂症和糖尿病的合并症：患病率，生活质量，身体健康，服务利用和成本。研究发现，在新的抗精神病药物广泛使用之前，糖尿病的诊断率就超过了一般人群的统计数据。糖尿病的危险因素与在一般人群中观察到的相似。糖尿病与身体健康状况不佳、医疗发病率以及服务使用和成本增加的联系需要引起注意。20世纪90年代早期的糖尿病研究表明，即使在非典型抗精神病药物广泛使用之前，糖尿病也是精神分裂症患者的主要问题。
People with schizophrenia may be at increased risk for Type II diabetes because of the side effects of antipsychotic medication, poorer overall physical health, less healthy lifestyles, and poorer health care. The present study uses data bases collected by the Schizophrenia Patient Outcomes Research Team (PORT) to assess the prevalence and demographic and clinical correlates of diabetes within large populations of persons receiving treatment for schizophrenia. In the Schizophrenia PORT, Medicaid and Medicare data from 1991 and more recent interview data were collected regarding the comorbidity of schizophrenia and diabetes: prevalence, quality of life, physical health, and services utilization and costs. The study found that rates of diagnosed diabetes exceeded general population statistics well before the widespread use of the new antipsychotic drugs. Risk factors for diabetes were similar to those observed in the general population. The linkage of diabetes to poor physical health, medical morbidity, and increased service use and cost requires attention. This study of diabetes in the early 1990s suggests that even before the widespread use of the atypical antipsychotic drugs, diabetes was a major problem for persons with schizophrenia.