Equating the PHQ-9 and GAD-7 to the HADS depression and anxiety subscales in patients with major depressive disorder

Equating the PHQ-9 and GAD-7 to the HADS depression and anxiety subscales in patients with major depressive disorder
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重性抑郁障碍患者PHQ-9和GAD-7与HADS抑郁和焦虑分量表的等值性研究

DOI:
10.1016/j.jad.2022.05.079
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发表时间:
2022-05-25
影响因子:
6.6
通讯作者:
Xu, Ming-Zhi
Xu, Ming-Zhi
中科院分区:
医学2区
文献类型:
--
作者:
Huang, Xiao-Jie;Ma, Hai-Yan;Xu, Ming-Zhi

文献摘要

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目的:本研究旨在将重度抑郁症(MDD)患者的9项患者健康问卷(PHQ-9)和7项广泛性焦虑症量表(GAD-7)分别与医院焦虑抑郁量表(HADS)抑郁和焦虑分量表(HADS-D、HADS-A)等同起来,并生成原始分数的人行横道。方法:由于它是单组设计,采用普通人采用等值法,共有460名MDD患者同时完成PHQ-9、GAD-7和HADS。采用Rasch分析筛选无效参与者,考察测试项目和参与者的心理测量属性,将PHQ-9与HADS-D以及GAD-7与HADS-A联系起来,并分别生成转换表。分析原始分数和转换分数之间的差异以验证人行横道。结果:抑郁部分的401个样本和焦虑部分的396个样本留作最终样本。 PHQ-9 / HADS-D 和 GAD-7 / HADS-A 组合分析都充分符合一维 Rasch 模型,证明了可接受的可靠性和项目人定位,并且没有显示无序类别。在项目 PHQ9 和项目 GAD6 中发现了不同性别的项目功能略有差异。生成人行横道并验证其有效性。局限性:结果可能仅限于在单个心理健康中心招募的 MDD 患者。结论:PHQ-9、GAD-7 和 HADS 抑郁和焦虑分量表成功链接,生成可用于直接将原始分数从一种仪器转换为另一种仪器的转换表。
Objective: The present study aimed to equate the 9-item Patient Health Questionnaire (PHQ-9) and 7-item Generalized Anxiety Disorder Scale (GAD-7) to the Hospital Anxiety and Depression Scale (HADS) depression and anxiety subscales (HADS-D,HADS-A) respectively in patients with major depressive disorder (MDD) and generate crosswalks of raw scores.Methods: As it is a single group design that adopts common-person equating method, a total of 460 patients with MDD completed the PHQ-9, GAD-7 and HADS at the same time. Rasch analysis was used to filter out invalid participants, investigate the psychometric properties of test items and participants, link the PHQ-9 and HADS-D as well as GAD-7 and HADS-A, and produce conversion tables respectively. The differences between original scores and converted scores were analyzed to validate the crosswalks.Result: 401 samples of depression part and 396 samples of anxiety part were left for final samples. Both the PHQ-9 / HADS-D and GAD-7 / HADS-A combined analysis adequately fit the unidimensional Rasch model, demonstrated acceptable reliability and item-person targeting and showed no disordering category. Slight differential item functioning across gender was found in item PHQ9 and item GAD6. The crosswalks were generated and verified to be validity.Limitations: The results might be restricted to patients with MDD recruited in a single mental health center.Conclusion: The PHQ-9, GAD-7 and HADS depression and anxiety subscales were successfully linked, producing conversion tables that could be used for directly converting raw score from one instrument to the other.