Prognostic Factors After Early Recurrence in Patients who Underwent Curative Resection for Hepatocellular Carcinoma
Prognostic Factors After Early Recurrence in Patients who Underwent Curative Resection for Hepatocellular Carcinoma
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DOI：
10.1002/jso.21786
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发表时间：
2011-02-01
影响因子：
2.5
通讯作者：
Hwang, Yoon Jin
中科院分区：
文献类型：
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作者：
Chun, Jae Min;Kwon, Hyung Jun;Hwang, Yoon Jin
背景资料：肝细胞癌（HCC）根治性肝切除术后早期复发的患者的预后通常是惨淡的。方法：124例患者在庆北国立大学医院从2002年1月至2006年12月接受了根治性肝切除术。早期复发定义为根治性切除术后2年内复发。结果：56例（45.2%）患者出现早期复发，其中12例（45.2%）患者出现早期复发。与早期复发相关的危险因素是肿瘤大小大于5 cm（P = 0.001）和存在肿瘤微转移（P <1.0 mg/dl）和肉眼可见血管浸润。（P = 0.004，P
Background: The prognosis of the patients with early recurrence after curative hepatectomy for hepatocellular carcinoma (HCC) is usually dismal.Methods: One hundred twenty-four patients underwent curative resection for HCC at Kyungpook National University Hospital from January 2002 to December 2006. An early recurrence was defined as a recurrence within 2 years after a curative resection. The risk factors associated with an early recurrence were analyzed as well as other risk factors correlated with survival after early recurrence.Results: Early disease recurrence developed in 56 patients (45.2%). The risk factors associated with an early recurrence were a tumor size larger than 5 cm (P = 0.001) and the presence of tumor micrometastasis (P1.0 mg/dl and macroscopic vascular invasion. (P = 0.004, P