The Human Genome Project and health behavior and health education research.
The Human Genome Project and health behavior and health education research.
复制标题
人类基因组计划与健康行为和健康教育研究。
DOI：
10.1093/her/8.4.589
复制
发表时间：
1993
影响因子：
2.4
通讯作者：
Cheuvront,B
中科院分区：
文献类型：
--
作者：
Sorenson,JR;Cheuvront,B
人类基因组计划（HGP）是一个多国计划，旨在绘制和测序人类基因组。这项重大的生物学研究工作估计需要15年时间，耗资30亿美元，对一般公共卫生，特别是对健康行为和健康教育研究，应该有重大的影响。预计人类基因组计划的研究将导致扩大（1）新生儿遗传病筛查，（2）产前诊断和（3）性状携带者筛查。人类基因组计划还可能导致对晚发型遗传病患者的症状前筛查，以及对由生活方式和环境因素之一或两者介导的常见疾病发病率和死亡率进行基于遗传的易感性筛查。这些潜在的发展引起了伦理、法律的和社会问题，并突出表明需要研究个人、组织、人口和政府如何利用和应对这些发展。遗传学在公共卫生中不断扩大的作用的核心将是健康行为和教育研究。这样的研究有助于有效和人道地应用人类遗传学。
The Human Genome Project (HGP) is a multinational initiative to map and sequence the human genome. This major biological research effort, estimated to take 15 years and cost $3 billion, should have significant implications for public health generally, and for health behavior and health education research in particular. It is anticipated that the HGP research will lead to expanded (1) newborn genetic disease screening, (2) prenatal diagnoses and (3) trait carrier screening. The HGP also is likely to lead to presymptomatic screening of people with late onset genetic diseases, as well as screening for genetic-based susceptibility for common disease morbidity and mortality mediated by either or both life style and environmental factors. These potential developments have raised ethical, legal and social questions, and have highlighted the fact that research is needed on individual, organizational, population and governmental use of and response to these developments. Central to the expanding role of genetics in public health will be health behavior and education research. Such research could contribute to an effective and humane applied human genetics.