Anticipation of moving stimuli by the retina
Anticipation of moving stimuli by the retina
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DOI：
10.1038/18678
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发表时间：
1999-03-25
期刊：
影响因子：
64.8
通讯作者：
Meister, M
中科院分区：
文献类型：
--
作者：
Berry, MJ;Brivanlou, IH;Meister, M
一道闪光会在30-100毫秒的时间内唤起大脑中的神经活动，这在很大程度上是由于光感受器中视觉传导的缓慢过程(2，3)。在这段时间内，一个移动的物体可以覆盖相当长的距离，因此应该在其实际位置的后面明显地被看到。由于这与日常经验相冲突，有人提出，视觉皮质使用眼睛延迟的视觉数据来推断运动物体的轨迹，以便在其实际位置被感知(4-7)。在这里，我们报告，这种对运动刺激的预期始于视网膜。一个移动的杆在视网膜神经节细胞群中引起一波尖峰活动。群体活动不是落后于视觉图像，而是在移动条的前缘附近移动。这种反应可以在很大的速度范围内观察到，显然可以补偿视觉反应的延迟。我们展示了这种预期是如何从已知的视网膜处理机制中得出的。
A flash of light evokes neural activity in the brain with a delay of 30-100 milliseconds', much of which is due to the slow process of visual transduction in photoreceptors(2,3). A moving object can cover a considerable distance in this time, and should therefore be seen noticeably behind its actual location. As this conflicts with everyday experience, it has been suggested that the visual cortex uses the delayed visual data from the eye to extrapolate the trajectory of a moving object, so that it is perceived at its actual location(4-7). Here we report that such anticipation of moving stimuli begins in the retina. A moving bar elicits a moving wave of spiking activity in the population of retinal ganglion cells. Rather than lagging behind the visual image, the population activity travels near the leading edge of the moving bar. This response is observed over a wide range of speeds and apparently compensates for the visual response latency. We show how this anticipation follows from known mechanisms of retinal processing.