Quantifying connectivity via efferent and afferent pathways in motor control using coherence measures and joint position perturbations
Quantifying connectivity via efferent and afferent pathways in motor control using coherence measures and joint position perturbations
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DOI：
10.1007/s00221-013-3545-x
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发表时间：
2013-07-01
影响因子：
2
通讯作者：
van der Kooij, Herman
中科院分区：
文献类型：
--
作者：
Campfens, S. Floor;Schouten, Alfred C.;van der Kooij, Herman
由于只有40- 50%的健康人群表现出显著的CMC，因此皮质肌相干性（CMC）作为连通性测量的适用性有限。在这项研究中，我们应用连续关节位置扰动，以获得更可靠的测量连接在电机控制。我们评估了关节位置扰动与EEG（位置-皮层相干性，PCC）和CMC之间的相干性。健康受试者进行了两个等张力任务对手柄的手腕机械手。基线任务是等距的;在扰动任务中，手柄以小幅度连续移动。位置扰动信号覆盖5和29 Hz之间的频率。在扰动任务中，所有受试者都有显着的PCC和86%的受试者有显着的CMC，在刺激和非刺激频率。在基线任务中，CMC仅存在于45%的受试者中，主要在β波段频率上。在等张力任务期间的位置扰动引起PCC在所有科目和引起CMC在大多数科目的刺激和非刺激频率。扰动CMC可能由两个独立的过程产生：一个内在过程，类似于未扰动任务中的过程，涉及传出和传入通路;以及一个与扰动引起的传入和传出通路的兴奋相关的过程。这些过程是无法分开的。然而，PCC仅反映通过传入通路的连接。由于PCC存在于所有健康受试者中，我们提出这种一致性作为通过传入通路进行运动控制的连接的可靠措施。
The applicability of corticomuscular coherence (CMC) as a connectivity measure is limited since only 40-50 % of the healthy population presents significant CMC. In this study, we applied continuous joint position perturbations to obtain a more reliable measure of connectivity in motor control. We evaluated the coherence between joint position perturbations and EEG (position-cortical coherence, PCC) and CMC. Healthy subjects performed two isotonic force tasks against the handle of a wrist manipulator. The baseline task was isometric; in the perturbed task, the handle moved continuously with small amplitude. The position perturbation signal covered frequencies between 5 and 29 Hz. In the perturbed task, all subjects had significant PCC and 86 % of the subjects had significant CMC, on both stimulus and non-stimulus frequencies. In the baseline task, CMC was present in only 45 % of the subjects, mostly on beta-band frequencies. The position perturbations during an isotonic force task elicited PCC in all subjects and elicited CMC in most subjects on both stimulus and non-stimulus frequencies. Perturbed CMC possibly arises by two separate processes: an intrinsic process, similar to the process in an unperturbed task, involving both efferent and afferent pathways; and a process related to the excitation of the afferent and efferent pathways by the perturbation. These processes cannot be separated. PCC, however, reflects connectivity via the afferent pathways only. As PCC was present in all healthy subjects, we propose this coherence as a reliable measure for connectivity in motor control via the afferent pathways.