Bladder melanosis with concurrent urothelial carcinoma.
Bladder melanosis with concurrent urothelial carcinoma.
复制标题
膀胱黑变病并发尿路上皮癌。
DOI：
10.1016/j.eucr.2017.09.001
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发表时间：
2017
影响因子：
0.5
通讯作者：
Johnson,MichaelH
中科院分区：
文献类型：
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作者：
Yau,SusannaE;Singer,EricJ;Sun,Yue;Johnson,MichaelH
3.膀胱黑变病是一种非常罕见的良性疾病。常见的症状包括血尿、尿失禁、尿潴留、排尿困难和尿频。由于报告的病例数量有限，这些症状必须在更多病例中与黑变病的存在联系起来，然后才能具体地被认为是病情的结果。这种情况发生在43岁至90岁的男性和女性中;所有病例都是偶然发现的。在报告人种的有限病例中，6例患者为高加索人，1例为非洲裔美国人。1应用丰塔纳马松、铁、高碘酸希夫等染色、漂白处理、S100蛋白和HMB 45免疫组化染色可辅助诊断。漂白后消失的黑色素通常存在于整个膀胱的黑色或棕色病变中。2
3. DiscussionMelanosis of the urinary bladder is an extremely rare, benign condition. Common symptoms found throughout these cases include hematuria, incontinence, retention, dysuria and urinary frequency. Due to the finite number of cases reported, these symptoms must be linked to the presence of melanosis in more cases before they can concretely be considered the result of the condition. The condition occurs in both men and women between the ages of 43 and 90; all instances have been discovered incidentally. In the limited number of cases where race was reported, 6 patients were Caucasian, while 1 was African American. 1 Applying stains such as Fontana Masson, iron, Periodic Acid Schiff, bleach treatment, and immunohistochemical stains for S100 protein and HMB45 can aid in diagnosis. Melanin pigment that disappears when bleached is typically found within the black or brown lesions found throughout the bladder. 2