Assessment of morbidity due to Schistosoma japonicum infection in China.
Assessment of morbidity due to Schistosoma japonicum infection in China.
复制标题
DOI：
10.1186/2049-9957-3-6
复制
发表时间：
2014-02-14
影响因子：
8.1
通讯作者：
Chen MG
中科院分区：
文献类型：
--
作者：
Chen MG
本文介绍了中国日本血吸虫感染发病率的历史评估。由于社会经济状况，直到20世纪50年代初才允许实施控制方案，在此之前发病率很严重，死亡率很高。根据一些调查和发表的论文，可以说这种疾病造成了数百万人死亡，摧毁了无数家庭和村庄。自20世纪50年代以来，我国制定了国家控制规划，加强了控制和预防工作，使该病得到了控制。目前，该病的患病率和发病率都在大幅度下降。本文概述了该病的三个阶段的发病情况。在疾病的急性期和晚期，发病率相对较高。四种主要形式的晚期血吸虫病，即腹水，巨脾症，侏儒症和结肠类肿瘤增生，概述了其特点的临床表现；它们的比例在国家控制计划的不同时期是不同的。本文还讨论了异位血吸虫病以及日本血吸虫感染与结直肠癌的关系。简要讨论了传播后血吸虫病（即使疾病达到消除标准，感染和传播已经停止，但仍会发展，也可能发生这种情况）。日本血吸虫的哺乳动物宿主问题使中国血吸虫病的流行病学和防治工作更加复杂和艰巨，本文简要介绍了动物宿主的防治进展。
This paper presents a historical assessment of morbidity due to the Schistosoma japonicum infection in China. Due to the socio-economic situation, which did not allow for a control program to be implemented until the early 1950s, morbidity was serious and mortality was high before this. Based on a few investigations and published papers, it can be said that the disease caused millions of deaths, and destroyed numerous families and villages. Since the 1950s, there has been a national control program, intensive control and prevention work has been carried out, and consequently the disease is being controlled. At present, both the prevalence and the morbidity of the disease have been decreasing substantially. The morbidity of the three phases of the disease is outlined in this paper. Comparatively higher morbidity is seen in the acute and advanced phases of the disease. The four major forms of advanced schistosomiasis i.e., ascites, megalosplenia, dwarfism, and colonic tumoroid proliferation, are outlined with their characteristic clinical presentations; their proportions are different during various periods of the national control program. Ectopic schistosomiasis and the relationship between the S. japonicum infection and colorectal cancer are also discussed. Post-transmission schistosomiasis is briefly discussed (which can happen even if the disease reaches the criteria of elimination, and the infection and transmission have stopped, but yet it still develops). The problem of mammalian reservoir hosts of S. japonicum makes the epidemiology and control of schistosomiasis in China even more complicated and arduous, and the control progress in animal reservoirs is briefly presented.
影响因子：
3.3
作者：
Fan, Ping-Chin
通讯作者：
Fan, Ping-Chin