Minimal tissue damage after stimulation of the motor thalamus in a case of chorea-acanthocytosis

Minimal tissue damage after stimulation of the motor thalamus in a case of chorea-acanthocytosis
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DOI:
10.1212/01.wnl.0000038389.30437.1e
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发表时间:
2002-12-24
期刊:
影响因子:
9.9
通讯作者:
Bioulac, B
Bioulac, B
中科院分区:
医学1区
文献类型:
--
作者:
Burbaud, P;Vital, A;Bioulac, B

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尸检结果来自一位患有舞蹈病-棘红细胞增多症的患者,该患者接受了运动丘脑深部脑刺激 (DBS) 治疗 2 年。术后测试显示轴性躯干痉挛逐渐改善。尽管该患者使用了相对较高的电流两年,但尸检分析显示电极尖端附近的组织损伤最小。结论是DBS对周围组织的影响很小。
Autopsy findings are reported from a patient with chorea-acanthocytosis treated for 2 years by deep brain stimulation (DBS) of the motor thalamus. Postoperative testing showed a progressive improvement in axial truncal spasms. Although relatively high currents were used for 2 years in this patient, postmortem analysis showed minimal tissue damage in the vicinity of the electrode tip. It is concluded that DBS has little impact on the surrounding tissues.