Single Breathhold Cardiac CINE Imaging With Multi-Echo Three-Dimensional Hybrid Radial SSFP Acquisition

Single Breathhold Cardiac CINE Imaging With Multi-Echo Three-Dimensional Hybrid Radial SSFP Acquisition
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DOI:
10.1002/jmri.22269
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发表时间:
2010-08-01
影响因子:
4.4
通讯作者:
Block, Walter F.
Block, Walter F.
中科院分区:
医学2区
文献类型:
--
作者:
Liu, Jing;Wieben, Oliver;Block, Walter F.

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目的:通过使用多回波三维 (3D) 混合径向 SSFP 采集来实现单屏气全心脏心脏 CINE 成像,提高空间分辨率和时间分辨率。材料和方法:使用多回波 3D 混合径向 SSFP 采集在单次屏气内获取心脏 CINE 成像。开发了一种优化的交错方案,用于在整个心动周期中进行视图排序。结果:在 17 秒屏气内,以 1.3 x 1.3 x 8.0 mm(3) 的空间分辨率和 45 ms 的时间分辨率获取全心短轴视图。通过测量整个心动周期的左心室容积并与传统的 2D 多次屏气技术进行比较,该技术在八名健康志愿者身上得到了验证。我们提出的 3D 技术与传统 2D 技术的左心室功能测量偏差:舒张末容积 -3.3 mL +/- 13.7 mL,收缩末容积 1.4 mL +/- 6.1 mL。射血分数 -1.7% +/- 4.3%,相应地具有较高相关性 0.94、0.97 和 0.91。结论:开发了多回波 3D 混合径向 SSFP 采集,以便在单次屏气中进行全心心脏 CINE 检查。志愿者的心脏功能测量结果优于标准多次屏气检查。
Purpose: To achieve single breathhold whole heart cardiac CINE imaging with improved spatial resolution and temporal resolution by using a multi-echo three-dimensional (3D) hybrid radial SSFP acquisition.Materials and Methods: Multi-echo 3D hybrid radial SSFP acquisitions were used to acquire cardiac CINE imaging within a single breathhold. An optimized interleaving scheme was developed for view ordering throughout the cardiac cycle.Results: Whole heart short axis views were acquired with a spatial resolution of 1.3 x 1.3 x 8.0 mm(3) and temporal resolution of 45 ms, within a single 17 s breathhold. The technique was validated on eight healthy volunteers by measuring the left ventricular volume throughout the cardiac cycle and comparing with the conventional 2D multiple breathhold technique. The left ventricle functional measurement bias of our proposed 3D technique from the conventional 2D technique: end diastolic volume -3.3 mL +/- 13.7 mL, end systolic volume 1.4 mL +/- 6.1 mL. and ejection fraction -1.7% +/- 4.3%, with high correlations 0.94, 0.97, and 0.91, accordingly.Conclusion: A multi-echo 3D hybrid radial SSFP acquisition was developed to allow for a whole heart cardiac CINE exam in a single breathhold. Cardiac function measurements in volunteers compared favorably with the standard multiple breathhold exams.