Is dose normalization to weight or body surface area useful in adults?
Is dose normalization to weight or body surface area useful in adults?
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根据体重或体表面积进行剂量标准化对成人有用吗？
DOI：
10.1093/jnci/82.4.323
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发表时间：
1990
期刊：
影响因子：
--
通讯作者：
Noe,D
中科院分区：
文献类型：
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作者：
Grochow,LB;Baraldi,C;Noe,D
讨论以前的审查已经确定了过去的成就和使用这些工具的机会（7，2）。然而，在这些试验的系列实施、评价和分析的共同标准达成一致之前，个体治疗的相对益处仍将有些混乱。希望这些建议的标准将作为一个刺激，以持续改善和共识的形成，使生活质量评估可以迅速实施到更大的随机临床试验，简单的统计分析，产生有效的结论。
DiscussionPrevious reviews have identified the past accomplishments and opportunities for use of these instruments (7, 2). However, until common criteria are agreed upon for the serial implementation, evaluation, and analysis of these trials, the relative benefits of individual treatment will remain somewhat confusing. It is hoped that these proposed criteria will serve as a stimulus to continued improvements and consensus formation so that quality-of-life assessments can be rapidly implemented into larger randomized clinical trials, with simple statistical analyses, resulting in valid conclusions.