Population receptive field dynamics in human visual cortex.

Population receptive field dynamics in human visual cortex.
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DOI:
10.1371/journal.pone.0037686
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发表时间:
2012
期刊:
影响因子:
3.7
通讯作者:
Morland AB
Morland AB
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Haak KV;Cornelissen FW;Morland AB

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90年代初的研究发现,当施加人工暗点时,猫初级视皮层神经元的视觉感受野可以发生位置和大小的变化。最近的研究表明,这些单神经元感受野动力学也属于神经元群体感受野(pRF),可以在人类中测量功能性磁共振成像(fMRI)。为了进一步研究这一点,我们估计了12名健康参与者的pRF,同时掩盖了视野的中心部分。我们发现,两个不同大小的人工暗点的位置和大小的pRF的变化,这些pRF动态最有可能是由于神经元感受野的位置和大小的散射以及调制反馈信号的组合从纹外视觉区。
Seminal work in the early nineties revealed that the visual receptive field of neurons in cat primary visual cortex can change in location and size when artificial scotomas are applied. Recent work now suggests that these single neuron receptive field dynamics also pertain to the neuronal population receptive field (pRF) that can be measured in humans with functional magnetic resonance imaging (fMRI). To examine this further, we estimated the pRF in twelve healthy participants while masking the central portion of the visual field. We found that the pRF changes in location and size for two differently sized artificial scotomas, and that these pRF dynamics are most likely due to a combination of the neuronal receptive field position and size scatter as well as modulatory feedback signals from extrastriate visual areas.
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