Human Papillomavirus Vaccination Series Initiation and Completion, 2008-2009

Human Papillomavirus Vaccination Series Initiation and Completion, 2008-2009
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DOI:
10.1542/peds.2011-0950
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发表时间:
2011-11-01
期刊:
影响因子:
8
通讯作者:
Markowitz, Lauri E.
Markowitz, Lauri E.
中科院分区:
医学2区
文献类型:
--
作者:
Dorell, Christina G.;Yankey, David;Markowitz, Lauri E.

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目的:目的是描述与人乳头瘤病毒(HPV)疫苗接种系列开始(>= 1剂量)和完成(>= 3剂量)以及父母给女儿接种疫苗的意图相关的因素。方法:分析2008年和2009年国家免疫调查-青少年的数据,以估计13至17岁女孩(N = 18 228)的HPV疫苗接种覆盖率,并检查疫苗接种覆盖率与人口统计学特征的关系。结果:总体而言,40.5%的女孩接种了>= 1剂HPV疫苗,53.3%的女孩完成了该系列疫苗接种。与开始接种疫苗独立相关的因素包括年龄较大、11至12年的预防性就诊、保险状况、母亲年龄和婚姻状况、未在公共设施接种所有疫苗以及提供者推荐,这是与开始接种疫苗最密切相关的因素(患病率:2.6[95%置信区间:2.4-2.9])。与白人女孩(60.4%)相比,黑人女孩(46.0%)和西班牙裔女孩(40.3%)完成该系列的可能性较小。缺乏疫苗知识(19.4%)、不需要接种疫苗(18.8%)、女儿性行为不活跃(18.3%)和提供者不建议(13.1%)是父母不打算让女儿接种疫苗的最常见原因。结论:尽管HPV疫苗接种率正在提高,但仍低于目标水平。提供者对青少年患者和家长的建议可能会提高疫苗的吸收率。在接触HPV疫苗之前,需要对父母进行有关疾病风险和益处的教育,以促进疫苗的吸收。儿科2011;128:830 - 839
OBJECTIVE: The goal was to describe factors associated with human papillomavirus (HPV) vaccination series initiation (>= 1 dose) and completion (>= 3 doses) and parents' intent to have their daughters vaccinated.METHODS: Data from the 2008 and 2009 National Immunization Survey-Teen were analyzed to estimate HPV vaccination coverage among girls 13 to 17 years of age (N = 18 228) and to examine associations of vaccination coverage with demographic characteristics.RESULTS: Overall, 40.5% of girls had received >= 1 HPV vaccine dose, and 53.3% of those girls completed the series. Factors independently associated with vaccination initiation included older age, having an 11- to 12-year preventive visit, insurance status, mother's age and marital status, not receiving all vaccines at public facilities, and provider recommendation, which was the factor most strongly associated with initiation (prevalence ratio: 2.6 [95% confidence interval: 2.4-2.9]). Compared with white girls (60.4%), black (46.0%) and Hispanic (40.3%) girls were less likely to complete the series. Lack of knowledge of the vaccine (19.4%), vaccination was not needed (18.8%), the daughter was not sexually active (18.3%), and a provider did not recommend (13.1%) were the most common reasons for parents' nonintent to have their daughters vaccinated.CONCLUSIONS: Although HPV vaccine coverage rates are increasing, they are still below target levels. Recommendations by providers to adolescent patients and parents likely would improve vaccine uptake. Parental education regarding disease risks and benefits of HPV vaccination before exposure is needed to promote vaccine uptake. Pediatrics 2011;128:830-839