Adaptive artificial evolution of droplet protocells in a 3D-printed fluidic chemorobotic platform with configurable environments.
Adaptive artificial evolution of droplet protocells in a 3D-printed fluidic chemorobotic platform with configurable environments.
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DOI：
10.1038/s41467-017-01161-8
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发表时间：
2017-10-26
影响因子：
16.6
通讯作者：
Cronin L
中科院分区：
文献类型：
--
作者：
Parrilla-Gutierrez JM;Tsuda S;Grizou J;Taylor J;Henson A;Cronin L
通过自然选择的进化是由环境中生物的持久性和繁殖所控制的。环境是重要的，因为它使生命得以出现，并塑造了今天的进化。虽然进化在从生物学到计算机科学的各个领域都得到了广泛的研究，但在计算机模拟之外，人们对环境变化对人工化学进化系统的影响仍然知之甚少。在这里，我们开发了一种全自动3D打印的化学机器人流体系统，该系统能够在真实的时间内生成和选择液滴原始细胞，同时改变它们进行人工进化的环境。该系统使用快速原型制作，并明确引入可编程环境作为实验变量。我们的研究结果表明，环境不仅作为一个积极的选择器的基因型，但也提高了能力，个别基因型进行适应，以应对环境压力。很少有研究探讨了变化的环境对人工化学进化的影响。在这里，作者开发了一个进化平台，改变了液滴原始细胞的物理环境，表明简单化学物种的种群可以适应其周围环境，类似于自然进化。
Evolution via natural selection is governed by the persistence and propagation of living things in an environment. The environment is important since it enabled life to emerge, and shapes evolution today. Although evolution has been widely studied in a variety of fields from biology to computer science, still little is known about the impact of environmental changes on an artificial chemical evolving system outside of computer simulations. Here we develop a fully automated 3D-printed chemorobotic fluidic system that is able to generate and select droplet protocells in real time while changing the surroundings where they undergo artificial evolution. The system is produced using rapid prototyping and explicitly introduces programmable environments as an experimental variable. Our results show that the environment not only acts as an active selector over the genotypes, but also enhances the capacity for individual genotypes to undergo adaptation in response to environmental pressures. Few studies have explored the effect of a changing environment on artificial chemical evolution. Here, the authors develop an evolutionary platform that alters the physical environment of droplet protocells, showing that a population of simple chemical species can adapt to its surroundings, in analogy to natural evolution.
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影响因子：
2.6
作者：
Eiben, A E;Kernbach, S;Haasdijk, Evert
通讯作者：
Haasdijk, Evert
影响因子：
64.8
作者：
Berut, Antoine;Arakelyan, Artak;Lutz, Eric
通讯作者：
Lutz, Eric
DOI：
10.1073/pnas.1619783114
发表时间：
2017-05-16
影响因子：
11.1
作者：
Jin, Chenyu;Krueger, Carsten;Maass, Corinna C.
通讯作者：
Maass, Corinna C.
DOI：
10.1073/pnas.58.1.217
发表时间：
1967-01-01
影响因子：
11.1
作者：
MILLS, DR;PETERSON, RL;SPIEGELMAN, S
通讯作者：
SPIEGELMAN, S
影响因子：
16.6
作者：
Browne, Kevin P.;Walker, David A.;Grzybowski, Bartosz A.
通讯作者：
Grzybowski, Bartosz A.