Postthrombectomy Systolic Blood Pressure and Clinical Outcome among Patients with Successful Recanalization
Postthrombectomy Systolic Blood Pressure and Clinical Outcome among Patients with Successful Recanalization
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DOI：
10.1159/000502519
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发表时间：
2019-11-01
影响因子：
2.4
通讯作者：
Han, Moon-Ku
中科院分区：
文献类型：
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作者：
Chang, Jun Young;Han, Moon-Ku
背景：动脉内血栓切除术(IAT)后的最佳血压(BP)管理尚未完全阐明。我们评估了IAT后24小时内是否维持130或130 mm Hg的收缩压(40.5比66.7%，p=0.02)。MRS在完全再通、基线侧支状态差(软脑膜动脉充盈评分0~3分)、心源性卒中或大脑中动脉闭塞的患者中的分布有显著差异，MRS值越高，平均SBP越高。IAT后24小时内平均SBP和GT；130 mm Hg与多变量调整后较差的功能结局相关(OR 2.66；95%CI 1.11-6.41；p=0.03)。结论：大血管闭塞患者在IAT后24 h内严格控制血压可改善再通成功的患者的临床预后。
Background: Optimal blood pressure (BP) management after intraarterial thrombectomy (IAT) has yet to be thoroughly elucidated. We assessed whether maintaining a systolic BP (SBP) of 130 or 130 mm Hg over the 24 h after IAT (40.5 vs. 66.7%, p = 0.02). The distribution of mRS varied significantly among patients with complete recanalization, poor baseline collateral status (pial arterial filling score 0-3), cardioembolic stroke, or middle cerebral artery occlusion, with higher mRS values associated with higher mean SBPs. A mean SBP >130 mm Hg during the 24 h after IAT was associated with worse functional outcomes after multivariable adjustment (OR 2.66; 95% CI 1.11-6.41; p= 0.03). Conclusion: Stricter BP control during the 24 h following IAT may improve clinical outcomes in patients with large vessel occlusion who achieved successful recanalization.