Trophoblast differentiation:: Progenitor cells, fusion and migration -: A workshop report

Trophoblast differentiation:: Progenitor cells, fusion and migration -: A workshop report
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DOI:
10.1016/j.placenta.2006.01.011
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发表时间:
2006-04-01
期刊:
影响因子:
3.8
通讯作者:
Knöfler, M
Knöfler, M
中科院分区:
医学3区
文献类型:
--
作者:
Aplin, JD;Straszewski-Chavez, SL;Knöfler, M

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未来的挑战在于揭开滋养层及其表达基因在正常人类胎盘发育、生长和病理中所起的作用。明确地需要具体的技术进步来描述功能的特性。特别是,在回答许多关键问题之前,需要改进体外模型。本文对滋养层细胞分化研究的最新进展进行了讨论。
Challenge lies ahead in unravelling the role played by trophoblast and its repertoire of expressed genes in normal human placental development, growth and pathology. Specific technical advances will clearly be required for characterisation of function. In particular, improvements in out, repertoire of in vitro models are needed before many of the key questions can be answered. Recent advances in the study of human trophoblast differentiation are discussed.