A Case of decapitated spermatozoa in an infertile man
A Case of decapitated spermatozoa in an infertile man
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DOI：
10.1111/j.1439-0272.1995.tb01089.x
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发表时间：
2009-04
期刊：
影响因子：
2.4
通讯作者：
Y. Toyama;T. Kazama;H. Fuse;T. Katayama
中科院分区：
文献类型：
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作者：
Y. Toyama;T. Kazama;H. Fuse;T. Katayama
摘要本文报告一例男性不育患者的无头或断头精子。这名33岁的患者除无头精子百分比较高（超过90%）外，精子造影几乎正常。低渗肿胀和无精子症仓鼠卵试验均表明，大多数无头精子的尾部功能似乎正常。采用表面复型法和常规电镜切片法对精子的超微结构进行了观察。无头精子除头部缺失外，其余结构基本正常。没有尾巴的头很少被观察到。在精子头部观察到多种超微结构异常。其中，覆盖核后极的核膜异常突出。植入窝和基板未形成。相反，在该区域发现了具有许多核孔的核膜。断头似乎发生在基板和近端中心粒之间。
Summary A case of headless or decapitated spermatozoa of an infertile man is reported. The 33‐year‐old patient showed almost normal spermi‐ogram except for a high percentage (more than 90%) of headless spermatozoa. Both hypoosmotic swelling and zona‐free hamster egg tests showed that most headless spermatozoa appeared to be normal in their function as tails. The ultrastructure of the ejaculated spermatozoa was observed using a surface replica method and by conventional ultrathin sectioning. The headless spermatozoa were almost normal in structure except for the absence of the head. Tailless heads were rarely observed. Varieties of ultrastructural abnormalities were observed in spermatozoa heads. Among them, abnormalities in the nuclear membrane covering the posterior pole of the nucleus were prominent. The implantation fossa and the basal plate were not formed. Instead, the nuclear membrane with numerous nuclear pores was found in this region. The decapitation seemed to take place between the region of the basal plate and the proximal centriole.