Efferent connections of the lamina terminalis, the preoptic area and the insular cortex to submandibular and sublingual gland of the rat traced with pseudorabies virus
Efferent connections of the lamina terminalis, the preoptic area and the insular cortex to submandibular and sublingual gland of the rat traced with pseudorabies virus
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DOI：
10.1016/s0006-8993(98)00765-3
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发表时间：
1998-09-28
期刊：
影响因子：
2.9
通讯作者：
Oldfield, BJ
中科院分区：
文献类型：
--
作者：
Hübschle, T;McKinley, MJ;Oldfield, BJ
神经元位于终板（终板，正中视前核和穹窿下器官的血管器），以及在内侧和外侧部分的视前区和岛叶皮质成为transneuronally标记后，伪狂犬病病毒注射到下颌下腺或舌下腺。这些神经元传出连接到一个链的中央神经元直接分泌或血管组织的下颌下腺或舌下腺。通过改变接种后的时间，不同的前脑核的逐步感染注册，下丘脑室旁核和下丘脑外侧区是第一个前脑结构标记。这些下丘脑核团内的早期感染神经元很可能是调节唾液分泌的三级神经元，并可能起到将病毒传递到其他前脑结构的中继作用。上述前脑区与下丘脑其他几个核团以及终纹床核、杏仁中央核和无名质等，似乎是唾液腺功能中枢调节的广泛解剖学基础。(C)1998 Elsevier Science B.V.保留所有权利。
Neurones situated in the lamina terminalis (organum vasculosum of the lamina terminalis, median preoptic nucleus and subfornical organ) as well as within medial and lateral parts of the preoptic area and in the insular cortex become transneuronally labelled following pseudorabies virus injections into the submandibular or the sublingual gland. These neurones are efferently connected to a chain of central neurones directed to secretory or vascular tissue of the submandibular or the sublingual gland. By varying the postinoculation time a stepwise infection of different forebrain nuclei was registered, with the hypothalamic paraventricular nucleus and the lateral hypothalamic area being the first forebrain structures labelled. Such early infected neurones within these hypothalamic nuclei are in all likelihood third order neurones regulating salivary secretion and might have functioned as relays transmitting virus to other forebrain structures. The above mentioned forebrain areas together with several other hypothalamic nuclei as well as the bed nucleus of the stria terminalis, the central nucleus of the amygdala and the substantia innominata, seem to be the widespread anatomical basis for the central regulation of salivary gland function. (C) 1998 Elsevier Science B.V. All rights reserved.