EXERCISE HYPERPNEA AND LOCOMOTION - PARALLEL ACTIVATION FROM THE HYPOTHALAMUS
EXERCISE HYPERPNEA AND LOCOMOTION - PARALLEL ACTIVATION FROM THE HYPOTHALAMUS
复制标题
运动时过度呼吸和运动--下丘脑的平行激活
DOI：
10.1126/science.7466362
复制
发表时间：
1981-01-01
期刊：
影响因子：
56.9
通讯作者：
WALDROP, TG
中科院分区：
文献类型：
--
作者：
ELDRIDGE, FL;MILLHORN, DE;WALDROP, TG
未麻醉的去皮质猫走或跑在跑步机上正常自发或在丘脑底运动区的电刺激。呼吸反应通常先于运动反应，并且尽管控制或消融呼吸反馈机制，但呼吸反应仍与运动活动成比例增加。尽管没有肌肉收缩或运动，但在虚构的运动过程中，瘫痪动物的呼吸也同样增加。因此，下丘脑命令信号主要负责运动和呼吸在运动过程中的比例驱动。
Unanesthetized decorticate cats walked or ran normally on a treadmill either spontaneously or during electrical stimulation of the subthalamic locomotor region. The respiratory response usually preceded the locomotor response and increased in proportion to locomotor activity despite control or ablation of respiratory feedback mechanisms. Respiration increased similarly in paralyzed animals during fictive locomotion despite the absence of muscular contraction or movement. Hypothalamic command signals are thus primarily responsible for the proportional driving of locomotion and respiration during exercise.